Hyperbilirubinemia is one of the most common causes of health problems, observed in 60% of term and 80% of preterm infants in the first week of life. Hyperbilirubinemia leads to neurotoxicity in severe condition. Some studies suggests that liberal use of oxytocin for inducing labour is one of the factor which lead to neonatal hyperbilirubinemia. OBJECTIVE: To compare the effect of oxytocin and neonatal bilirubin levels with spontaneous vaginal delivery. MATERIALS AND METHODS: 100 full term parturients were selected for this study. The subjects were divided into two groups. 50 healthy babies of women who had oxytocin induced labour and 50 healthy babies of women with normal vaginal delivery following spontaneous onset of labour formed the control group. Neonatal serum bilirubin was measured on day 1, 3 and 5 after delivery. Bilirubin was measured by spectrophotometry. Data was analysed in ms excel sheet using spss 19.0v. Statistical analysis was done by using unpaired't' test. RESULTS: There was significant increase in bilirubin level in oxytocin induced group compared to control group on day 1 and 3. There was insignificant increase in bilirubin level in oxytocin induced group on day 5. However the level of serum bilirubin is within normal limits as bilirubin level normally rises on till 4 th day and decreases thereafter. CONCLUSION: Neonatal hyperbilirubinemia may be due to oxytocin administration by continues IV infusion which results in erythrocyte swell and rupture. Increase in bilirubin level in oxytocin induced group is within physiological limits.
BACKGROUND AND OBJECTIVES: With advancing age, degenerative changes occur in heart muscle and its conduction system. This study was undertaken to see the ECG changes in different age groups of healthy adults. MATERIALS & METHODS: A cross sectional study was conducted in a group consisting of 150 (75 male and 75 female) Healthy adults in the age group 21 to 80 years. All the subjects were divided into different subgroups according to their sex and age. Lead II ECG was recorded on all subjects in supine position in an ambient temperature for 3 minutes by using Power lab. And the analysis of the ECG was done by the software in the same instrument. RR interval, Heart rate and ST height were used for analysis. RESULTS: There was prolongation of R-R interval and decrease in heart rate and ST height with increasing age in both males and females. CONCLUSION: In this study we saw changes in different ECG parameters in both males and females of different age groups. There were changes in some of the ECG parameters between males and females of different age groups. But all these changes were within physiological limits.
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