Aim: To evaluate the clinical efficacy of subgingivally delivered SMV and Placebo gel and compare in the treatment of stage II periodontitis when used as an adjunct to SRP and their antimicrobial effect on the Porphyromonas gingivalis bacteria. Materials & Methods: In a split mouth study design, 10 systemically healthy patients with stage II periodontitis were included in this study based on the inclusion and exclusion criteria. Two sites with deepest pockets were selected. Plaque samples were collected from these pockets at baseline followed by full mouth scaling and root planning, In Group I 1,2% SMV gel and in Group II Placebo gel was placed in the subgingival pockets. Microbiological analysis for Colony Forming Units of P.g was done at baseline after 3 months, Clinical parameters (GI, PI, PD, CAL, mSBI) were evaluated at baseline (before SRP), 1 month and 3 months. Result: Both the groups showed significant reduction in GI, PI, PD, CAL, mSBI and CFU of Pg but Group I showed more significant reduction than Group II.
Purpose: Dentinal hypersensitivity is a common clinical condition associated with exposed dentinal surfaces. Dentinal tubules can be entirely blocked after irradiation by 980-nm diode laser, with no significant morphological alterations after radiation. The use of toothpastes containing Potassium Nitrate and Calcium Hydroxyapatite reduces dentinal hypersensitivity. The main purpose of this study was to evaluate and compare the efficacy of Diode Laser and two Desensitizing Toothpastes for Dentinal Tubular Occlusion by Scanning Electron Microscopy (SEM). Methods: Twelve extracted premolars were divided into two halves each obtaining twenty-four dentin discs. Specimens were etched with 17% phosphoric acid to expose the tubules and were divided into four groups: i.e., Group A: Application of Diode Laser, Group B: Application of SHY-XT toothpaste, Group C: Application of Biomed toothpaste and Group D: Application of Distilled water. After treatment, quantitative analysis of occluded dentinal tubules was done by SEM analysis. Results: The mean values of total dentinal tubular occlusion in Groups A, B, C and D were 0.42, 0.86, 2.14, 4.07 respectively which was statistically significant (p<0.001*). Diode laser (Group A) yielded a significant occlusion of the dentinal tubules when compared to the two desensitizing toothpastes (Groups B and C).
BACKGROUND: Periodontal disease is associated with colonization of specific bacteria in the subgingival area. Widespread use of antimicrobials has resulted in emergence of various side effects and drug resistance. Phytomedicine has been used in many clinical conditions and it appears to be a suitable alternative to manage conditions affecting the oral cavity. AIM: Present study aims to assess the in-vitro antimicrobial efficacy of Tulsi extract and Curcumin extract on Periodontal pathogens. MATERIALS & METHODS: Ethanolic extract of 100% w/v of Tulsi and Curcumin was prepared by cold extraction technique. Prepared extracts were further diluted to obtain solutions of 5 different concentrations to be tested (0.5%, 1%, 2% and 5%). Obtained solutions and controls (0.2% Chlorhexidine and Distilled water) were subjected to the microbiological investigation against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Agar well diffusion method was employed to determine the concentration at which Tulsi and Curcumin gave an inhibition zone, similar to Chlorhexidine. Data was analysed using one‑way analysis of variance and post‑hoc test for inter-group and intra‑group comparisons. RESULTS: At 10% concentration both Tulsi and Curcumin extract have demonstrated comparable antimicrobial activity against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis.
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