C225 has dose-dependent pharmacokinetics, and doses that achieve saturation of systemic clearance are well tolerated. C225 given in combination with cisplatin has biologic activity at pharmacologically relevant doses.

Research on fathers has increased substantially over the last several decades, but research comparing the gender-typed characteristics and gender role attitudes of stay-at-home and employed fathers is still in its infancy. Stay-at-home (n = 35) and employed (n = 49) fathers completed measures on gender-typed characteristics and gender role attitudes. Stay-at-home fathers also rated the importance of various reasons they stayed home. Compared to employed fathers, stay-at-home fathers reported similar levels of traditional feminine and masculine characteristics, but less traditional gender role attitudes. Wanting to be a stay-at-home father was rated the most important reason for staying home. The more important the female partner was in influencing the decision to stay home, the lower the levels of masculine characteristics and the more enjoyment men reported in being a stay-at-home father. Future research should focus on comparisons of paternal involvement in stay-at-home and other fathers, the reasons men decide to become or not to become stay-at-home fathers, and the factors that influence those reasons, such as their partners' attitudes and experiences with prejudice and discrimination.

Recent events have drawn attention to the prejudice and discrimination faced by transpeople; however, there is limited research on attitudes toward transpeople. We studied the effects of facial appearance on the evaluations of transsexuals in 239 heterosexual undergraduate students from the midwestern United States. Men had significantly more negative evaluations than women. The gender of the transsexual (male-to-female or female-to-male) had limited effects on evaluations; however, the transsexual whose facial appearance was congruent with their desired gender was perceived as more attractive than the transsexual whose facial appearance was incongruent. Negative evaluations were correlated with higher levels of transphobia and sexual prejudice. Further investigation is needed on the factors that influence prejudicial attitudes toward transpeople, including physical appearance.

Although significant progress has been made on research concerning stereotypes of feminist women, very little is known about the stereotypes of feminist men. College students rated one of four terms—“feminist man,”“feminist woman,”“man,” or “woman.” Compared to “feminist woman,”“feminist man” was evaluated more positively, but as less potent (i.e., lower in stereotypically masculine characteristics) and less heterosexual. Although feminist man had the highest evaluative ratings of the four terms and was rated similarly in confidence to woman and man, compared to the other terms it was rated low in attractiveness and potency. These results suggest that at least on some dimensions a feminist man's masculinity may be questioned, which in turn may be a hindrance to men in adopting the feminist label.

The “just world” hypothesis has been used to explain victim blaming, or the attributions that people have for why a person has been victimized. Based on some of the premises of the just world hypothesis it was predicted that people would be more likely to attribute blame to a gay man with AIDS than they would to a heterosexual man with AIDS. From a sample of 79 undergraduate students it was found that a gay man was given more personal blame for contracting AIDS than a heterosexual man. Furthermore, the more intolerant people were towards gay men and the more fearful they were of contact with AIDS, the more likely they were to blame the gay man for contracting AIDS. Although preliminary, these results indicate the usefulness of the just world hypothesis for understanding the stigmatization of people with AIDS.