The
synthesis of novel asymmetrically substituted cobalt complexes
of the type [Co(CO)(NO)(NHC)(PR3)] (NHC =
i
Pr2Im, PR3 = PMe3 (1), PEt3(2), PH
i
Pr2 (3); PR3 =
PMe3;, NHC = Me2ImMe (4), Me
i
PrIm (5), Me
t
BuIm (6),
i
Pr2ImMe (7); R2Im =
1,3-dialkylimidazolin-2-ylidene) is reported. These complexes are
stabilized by N-heterocyclic carbene (NHC), phosphine, carbonyl, and
nitrosyl ligands and have been synthesized from the reaction of a
NHC-substituted precursor of the type [Co(CO)2(NO)(NHC)]
and the corresponding phosphine. The synthesis of [Co(CO)(NO)(Me
t
BuIm)(PMe3)] (6)
and [Co(CO)(NO)(
i
Pr2ImMe)(PMe3)] (7) proceeds in a thermal
reaction even at room temperature by quantitative replacement of one
carbonyl with a phosphine ligand. All of the other complexes were
synthesized using photochemical conditions. Complexes 1–6 have been characterized by elemental analysis,
IR spectroscopy, and multinuclear NMR spectroscopy and in some cases
by X-ray crystallography. All complexes are volatile, are stable upon
sublimation, and decompose readily in a stepwise manner at elevated
temperature. The complex [Co(CO)(NO)(
i
Pr2Im)(PMe3)] (1) as well as cobalt
complexes that were reported earlier, i.e. [Co(CO)(NO)(
i
Pr2Im)2], [Co(CO)(NO)(Me
t
BuIm)2], and [Co(CO)2(NO)(
i
Pr2Im)], are evaluated
and have been successfully applied in the deposition of cobalt-based
thin films.
The crystal structure of e-rhamnose monohydrate has been refined with three-dimensional data, obtained on an automatic computer-controlled Siemens four-circle diffractometer using Cu Ke radiation. Refinement was by the least-squares method using an absolute weighting scheme. The initial coordinates were those of McGeachin & Beevers [Acta Cryst. (1957)
The title compound, 5-chlorospiro[indoline-3,7'-pyrano[3,2-c:5,6-c']dichromene]-2,6',8'-trione was synthesized via one-pot pseudo three-component reaction between one equivalent of 5-chloroisatin and two equivalents of 4-hydroxycoumarin using mandelic acid as catalyst in aqueous ethanol at 110 °C. The synthesized compound was characterized by FT-IR, 1H NMR, and HRMS techniques. Single crystals were grown for crystal structure determination by using single X-ray crystallography technique. It was found that the crystals are triclinic with space group P-1 and Z = 1. The crystal structure was solved by direct method and refined by full-matrix least-squares procedures to a final R-value of 0.0688 for 6738 observed reflections. The crystal structure was stabilized by elaborate system of O-H···O, N-H···O, and C-H···O interactions with the formation of supramolecular structures. 3D Hirshfeld surfaces and allied 2D fingerprint plots were analyzed for molecular interactions. Molecular docking studies have been performed to get insights into the inhibition property of this molecule for Human topoisomerase IIα.
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