Asphaltenes are a solubility class of petroleum crude oil that can destabilize and deposit in both upstream and downstream processes. In this study, asphaltene deposits were generated in metal capillaries by heptane addition to crude oils, and it was found that deposition is caused by submicrometer asphaltene aggregates. Deposits were generated at heptane concentrations above and significantly below the instantaneous onset point. Analysis of the results reveals that the governing factor controlling the magnitude of asphaltene deposition is the concentration of insoluble asphaltenes present in a crude oilprecipitant mixture and the instantaneous onset point is irrelevant to the deposition process. Electron microscopy images of the deposits represent the first images and confirmation of arterial growth in laboratory generated asphaltene deposits. The axial deposit profile was found to be highly nonuniform. In addition, deposits formed shortly after when oil and heptane mix, revealing that the destabilization of asphaltenes occurs virtually immediately after a precipitant is added. The results were reproduced with a second crude oil, indicating that asphaltene deposition behavior is broadly applicable.