Cu-thioneins isolated from liver and brains are able to transfer their copper atoms to apoforms of neurocuprein 1 and 2. At the same time, the apoform of Cu-thionein is unable to accept copper from holoforms of both neurocupreins.
Immunoassay on polymeric particles with covalently bound N-acetyl glucosamine was applied for detection of appropriate antibodies. Antibodies to N-acetyl glucosamine were detected in sera of patients with multiple myeloma. The assay was conducted on polymeric microparticles by enzyme immunoassay. The sensitivities of the assays on microparticles and on glass microtubes were compared. It was shown that the level of antibodies to N-acetyl glucosamine correlated with the number of myeloma cells. The comparison of assays on microparticles and glass tubes demonstrate the advantage of microparticle technology.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.