Background: As per Ayurvedic classics apeenasa is one of the nasagata rogas (nasal disorders) that be considered as the paranasal sinusitis according to the conventional medicine. The terms peenasa and apeenasa can be used based on the stages and the types of paranasal sinusitis. Objectives: To evaluate the efficacy of nasya karma (nasal instillation therapy) and vyoshadi vati in patients of apeenasa having nasasrava (nasal discharge), shirogurutwa (heaviness of head) and kshavatu (sneezing) of patients suffering from apeenasa. Design: This was a randomized controlled study with thirty patients divided into three groups, 10 in each. In Group A, Nasya karma was given once a day for 7 days, in Group B, Vyoshadi vati was given twice a day for 7 days and in Group C, Nasya karma and Vyoshadi vati was given in combination for 7 days. Results: Statistically significant results were seen in reduction of nasasrava, shirogurutwa and kshavatu of patients suffering from apeenasa with p<0.001. Conclusions: Group C (Nasya karma with vyoshadi vati) showed statistically significant results compared to Group A (nasya karma) and Group C (Vyoshadi vati) in reduction of nasasrava, shirogurutwa and kshavatu of patients suffering from apeenasa.
The most common malignant neoplasm of salivary gland origin is mucoepidermoid carcinoma (MEC), and it comprises of about 5-10% of all salivary gland neoplasm. It is mostly seen in major salivary glands (54%) and two third of them occurs in the parotid gland, and 46% is seen in minor salivary glands. Histo-morphological complexity of MEC has a constellation of varying amount of epidermoid cells, goblet cells, intermediate cells and mucocytes. It is graded histopathologically based on the relative proportion of cell type, cystic spaces, degree of tumor invasion, anaplasia, mitotic rates and presence or absence of necrosis into low-grade, Intermediate grade and high-grade. In the literature, several variants of MEC such as conventional, clear cell, warthin-like, sclerosing and unicystic variant have been reported. The aim of the current case report is to present a low-grade variant of unicystic MEC which is rare, but a distinctive tumor affecting the salivary gland. Till date, to the best of our knowledge only one case has been reported.
Sinusitis is defined as the inflammation of the mucosa either of any one or all of the paranasal sinuses. In humans, there are four paired sinuses which are termed as paranasal sinuses and they are maxillary, frontal, ethmoid and sphenoid sinuses. Ayurveda being an ancient holistic science aims at alleviating the disease and protection and prevention of the positive health. Shalakya Tantra is one of the Astangas of Ayurveda that deals with the Uttamanga and the diseases related to Urdhvajatru. Paranasal sinusitis, the most common disease in Shalakya tantra can be correlated to the disease Apeenasa, Peenasa, Dusta Pratishyaya etc in Ayurveda based on its signs and symptoms. Apeenasa and Peenasa are used interchangeably for paranasal sinusitis in Ayurveda and they are managed with Deepana Pachana, Vamana, Virechana, Dhumapana, Nasya Karma or Shirovirechana. Nasya Karma, one of the Panchakarma therapy and the best therapy for the Urdhwajatrugata Rogas plays a vital role in the successful management of the sinusitis. In this therapy, the medicine is administered through nose either in the form of ghee, oil, powder, liquid or smoke. It is particularly useful in the treatment of diseases occurring in the organs situated above the clavicle but indirectly it works on the whole body by improving the functioning of the endocrine glands and nervous system.
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