Objective: To test the hypothesis that short-and long-term celecoxib administration has no effect on orthodontic tooth movement. Materials and Methods: Male Wistar rats were submitted to short-(3 days) and long-term (14 days) celecoxib administration, while the respective control groups received equivolumetric saline intraperitoneal injections. The upper left first molars of all rats were moved mesially for 14 days by a fixed orthodontic appliance exerting 50 g force upon insertion. After the experimental period, tooth movement was quantified and tissues around the first molar were processed for tartrateresistant acid phosphatase (TRAP) histochemistry. The amount of tooth movement and the number of TRAP-positive cells on the alveolar bone surface were evaluated. Results: The amount of tooth movement was significantly reduced in rats submitted to short-and long-term celecoxib administration, while the number of osteoclasts on the alveolar bone did not differ between the four groups studied. Conclusions: The hypothesis is rejected. Although celecoxib administration did not affect the number of osteoclasts, the osteoclast activity might be reduced, which could explain the inhibition of tooth movement observed in the celecoxib-treated animals. These results indicate that orthodontists should be aware of patients under short-and long-term therapy with celecoxib.
The results were submitted to descriptive analysis (mean and standard deviation), test F and "t" Student test with significance level of 5%. There was no significant difference between the group with nasal breathing and the group with predominantly mouth breathing for any of the studied variables.
Aim: to evaluate the possible correlation between the respiratory pattern in determining the craniofacial dimensions, using as baseline the Tweed-Merrifield's cephalometric analysis, added to angle SN-GoGn and to Y axis angle.
Methodology:The selected sample to this study comprised 50 teleradiographies taken in lateral and natural positions of the head in young female patients at the age of 9 to 12 years, presenting mean age of 10 years and 5 months and Class 1 malocclusion. After diagnosis of respiratory pattern, the sample was divided into two groups: control group, 25 teleradiographies of nasal breathers in lateral and natural positions of the head; experimental group, 25 teleradiographies of predominantly mouth breathers in lateral and natural positions of the head. Results: The results were submitted to descriptive analysis (mean and standard deviation), test F and "t" Student test with significance level of 5%. There was no significant difference between the group with nasal breathing and the group with predominantly mouth breathing for any of the studied variables.
OBJETIVO: avaliar a relação entre a correção ortodôntica da mordida cruzada posterior dentária e as alterações no padrão da atividade dos músculos masseter e temporal. METODOLOGIA: os autores estudaram vinte jovens de ambos os gêneros, leucodermas, entre 7 a 9 anos de idade, ortodôntica e eletromiograficamente. Todos apresentavam mordida cruzada posterior dentária, corrigida com aparelhos ortodônticos removíveis. A análise eletromiográfica bilateral dos músculos masseter e temporal ocorreu na condição de repouso e de mastigação aleatória, bem como antes da colocação do aparelho removível, 1 mês após o início do uso do aparelho, imediatamente após a correção da mordida cruzada e 1 mês após a retirada do aparelho. RESULTADOS: a análise dos dados obtidos mostrou que após 1 mês do início do tratamento ocorreu uma leve diminuição da atividade muscular do masseter em repouso, aumentando sua atividade logo após e mantendo-se alta um mês depois do tratamento ortodôntico. Durante a mastigação aleatória seus valores indicaram melhora em sua atividade. A atividade dos músculos temporais diminuiu um mês do início da terapia ortodôntica e permaneceu baixa logo após e um mês depois do tratamento ortodôntico. CONCLUSÃO: os dados sugerem que os músculos masseter e temporais apresentaram uma melhora de sua atividade em decorrência do tratamento ortodôntico.
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