Bioinformatics experiments are typically composed of programs in pipelines manipulating an enormous quantity of data. An interesting approach for managing those experiments is through workflow management systems (WfMS). In this work we discuss WfMS features to support genome homology workflows and present some relevant issues for typical genomic experiments. Our evaluation used Kepler WfMS to manage a real genomic pipeline, named OrthoSearch, originally defined as a Perl script. We show a case study detecting distant homologies on trypanomatids metabolic pathways. Our results reinforce the benefits of WfMS over script languages and point out challenges to WfMS in distributed environments.
O aumento na intensidade dos fluxos migratórios humanos pode ser observado desde o advento da modernidade, e cada vez mais pessoas procuram melhores condições de vida em outros países quando seu bem-estar se encontra ameaçado. No caso do subcontinente sul-americano cada vez mais tem crescido a imigração dentro da região e a tendência dos países de destino é de adotar medidas cada vez mais restritivas para impedir a entrada desses imigrantes, contrariando os catálogos normativos dos direitos humanos. O presente trabalho visa a analisar a situação migratória dos países nessa região e a investigar as legislações vigentes sobre o assunto.
DOI:10.5585/rdb.v5i3.112
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