Background: A prospective study was conducted to compare the effectiveness of Nifedipine and Isoxsuprine in suppression of preterm labour pain as tocolytics drug. As preterm labour pain is major contributor for perinatal morbidity and mortality. The aims of this study were to assess the effect of nifedipine and isoxsuprine in threatened preterm labour with the aim of preventing preterm birth and its sequelae.Methods: This study was conducted on 100 patients coming to Pannadhay Rajkiya Mahila Chikitsalaya, RNT Medical College, Udaipur and attending OPD and IPD with complain of uterine contractions between 28-36 weeks of gestation.Results: Nifedipine was more effective than isoxsuprine hydrochloride as tocolytic agent.Conclusions: There is high incidence of preterm labour in India which leads to neonatal morbidity and mortality. Nifedipine is a better tocolytic drug compared to isoxsuprine hydrochloride.
Background: Uterus, a vital reproductive organ is subjected to many benign and malignant diseases. Although many medical and conservative surgical treatment options are available, hysterectomy still remains the most commonly performed major gynaecological operative procedure worldwide. Mostly it is the definitive treatment for many of its indications including abnormal uterine bleeding, like in case of fibroids, adenomyosis, utero-vaginal prolapse, endometriosis and pelvic inflammatory disease. Aims and objectives were to know the indications for hysterectomy and its various complications and to analyse correlation between the clinical indication with their histopathological findings.Methods: This hospital based study was conducted at RNT Medical College, Udaipur. A total of 200 case were included undergoing hysterectomy (any route) for gynecological disease. Surgical specimens were sent for histopathology and reports were analysed and compared with the indications of surgery.Results: In this study preoperative indication of hysterectomy was leiomyoma (34.50%) followed by utero vaginal prolapse (39.0%) and adenomyosis (12.5%) etc. Common finding of HPR report of specimens of uterus and adnexa are as follows: endometrium- proliferative phase (44.50%), myometrium- leiomyoma (33%), cervix- mild squamous hyperplasia (45%), ovaries- physiological ovarian cyst (25.50%). Pre-operative diagnosis of all cases of study were confirmed on histopathology. There was no major intraoperative complication in study group like bladder, rectum, ureter, visceral organ injuries etc. There was no life-threatening postoperative complication and all patients were discharged in good general condition.Conclusions: In most cases diagnosis by HPR was similar with our preoperative diagnosis but in few cases HPR diagnosis may differ from preoperative diagnosis. Major complications were negligible, hence now-a-days hysterectomy is considered quite a safe procedure.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.