Background:The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pandemic has caused a re-emergence of tuberculosis (TB). In persons infected with both HIV and TB, the lifetime risk of developing TB disease is 50–70% compared to 10% in HIV-negative individuals. India has world's 3rd highest HIV burden and is also one of the countries endemic for TB, so the country faces a dual epidemic of HIV and TB.Objectives:To find out the proportion and determinants of TB in HIV-positive subjects.Subjects and Methods:This study was undertaken at the ART center from June 01, 2012, to May 31, 2013. HIV-positive subjects aged above 15 years who had been on antiretroviral therapy (ART) for more than 6 months were included in the study. Nonprobability purposive sampling was adopted. A predesigned semi-structured questionnaire was used to obtain data.Results:A total of 536 HIV-positive people were interviewed, 58.8% of whom were males, 79.1% were Hindu, 61.0% had up to high school education, and 57% were unskilled laborers. About 63% were married, 40% were from the upper lower class, and 60% were from urban areas. For the majority (89.1%), the probable mode of transmission of HIV was by the heterosexual route. TB co-infection was present in 38.4% subjects. The most common form of TB was extra-pulmonary in subjects on antituberculous treatment (47.3%) and among old cases (57.6%). On bivariate analysis, 136 (42.4%) married subjects and those from rural areas were more commonly affected by TB compared to subjects who were unmarried and from urban areas with odds ratio (OR): 1.555, confidence interval (CI): 1.077–2.246 and OR: 1.523, CI: 1.061–2.185, respectively. The proportion of TB was high among subjects who lived in overcrowded houses 130 (44.2%), and who had a habit of alcohol use compared to others with OR: 1.731, CI: 1.734–2.179 and OR: 1.524, CI: 1.045–2.223, respectively. Logistic regression analysis showed that TB among people living with HIV/AIDS was highest in persons living in overcrowded houses (OR: 1.706, CI: 1.185–2.458) and those who consumed alcohol (OR: 1.605, CI: 1.090–2.362).Conclusions:Demographic factors like male gender, middle age, living in the rural areas, consumption of alcohol, and living in overcrowded houses were found with a higher proportion of TB. The use of highly active ART appeared to progressively decrease but did not completely eliminate the risk of TB.
Background:Cortical venous thrombosis (CVT) is a rare condition, compared to arterial stroke and often occurs in young individuals presenting with varying clinical features.Aim:The aim is to study clinical profile and assess the outcome and prognostic factors of CVT patients.Methodology:A case series study was done for 2 years. CVT cases confirmed by magnetic resonance imaging were included in this study. Clinical presentation and risk factors were noted then patients were assessed at the time of discharge for their physical and mental status. Modified Rankin scale was used to group patients, accordingly scores 0–2 were considered as good and 3–6 as poor outcome, respectively. Data were analyzed using Chi-square test to know the association between prognostic factors and outcome.Results:Out of 81 patients, more than half of the patients were in the age group of <35 years (55.6%), and majority of patients were females (79%). Most common symptom was headache (82.7%) and least was fever (14.8%). Superior sagittal sinus was most commonly involved (74.1%). Nearly half of the patients were in puerperal period (44.1%). Patients aged more than 35 years (odds ratio [OR]: 9.1, confidence interval [CI]: 4.463–19.750) presenting with symptoms such as fever (OR: 3.442, CI: 1.088–12.140), impaired consciousness (OR: 5.467, CI: 2.064–15.330) and having clinical signs such as coma (OR: 23.99, CI, 3.844–544.1), papilledema (OR: 25.15, CI: 7.565–101.5), and with focal neurological deficit (OR: 9.366, CI: 2.693–3.41) had statistically significant poor outcome.Conclusion:Females formed a major bulk of patients. Higher number patients showed poor outcome. Study showed association between age, headache, impaired consciousness, coma, papilledema, and neurological deficit to poor outcome.
BACKGROUND: After China, it has been estimated by the WHO that India would have second largest number of smokers in the world. The National Family Health Survey-3, 2005-06, data revealed that 57% of adult men and 3.1% of adult women used one or more tobacco products. Among adolescent students the Global Youth tobacco survey 2006 estimated that 17.3% of boys and 9.75 % of girls in India are tobacco consumers. Most common to start tobacco consumption was peer pressure and curiosity. OBJECTIVES: 1) To study the socio-demographic profile of Tobacco consumers in Bellary 2) To find the factors attributing to initiation Tobacco consumption in Bellary. MATERIAL AND METHODS: A cross sectional study was conducted among 600 tobacco consumers (Both smoke & smokeless form) in Bellary from January 2011 to June 2011. In this Purposive sampling method was used to get the study subjects from each ward. A pre-tested and semi-structured proforma was used to collect the information. RESULTS: In the present study out of 600 subjects majority were belong to age group 19-45 years (59.1%), were literate (58.6%), 64.2% were using tobacco since more than ten years, around one third of the study subjects had started using tobacco before the age of 18 years. Peer pressure (49%) was the most common reason to initiate tobacco consumption. CONCLUSION: Tobacco consumption was more among literates. Many people had started consuming tobacco in there early age only. Peer pressure was the most common reason to initiate tobacco consumption.
Background: During pregnancy and child birth women are very much vulnerable to sickness and complications. Maternal morbidity and mortality can be reduced by giving proper preventive and promotive health care specially by promoting early registration, regular antenatal check-ups and institutional deliveries. There is an improvement in care since last decade. Still there is a long way in achieving complete success out of these National programmes.Methods: A cross-sectional study was done in six Anganawadi centres in rural field practice area of medical college for a period of 4 months from 1st June 2017 to 30th September 2017. Universal sampling was adopted to include all registered pregnant women. Informed consent was taken. A pre-designed semi-structured questionnaire was used to collect data. Appropriate descriptive statistics like proportion and percentage were used describe and to draw the inferences.Results: A total of 104 pregnant women were included. Most of them were in the age group of 20 to 30 years 76 (73.1%). More than half were in third trimester 60 (57.7%), seeking antenatal care from both government and private facilities equally. Awareness about various schemes ranged from minimum of 2 (1.9%) for JSSK to maximum of 102 (98.1%) for ICDS. ASHA workers 96 (92.3%) acted as source of information for majority of pregnant women followed by Anganawadi workers 88 (84.6%).Conclusions: Knowledge was adequate but not sufficient across all schemes hence more efforts should be done to overcome this discrepancy. Health care workers like ASHA and Anganawadi worker have put efforts in creating awareness.
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