Synthesis of C5-Substituted Imidazolines. -The pharmacologically interesting title compounds are prepared by Mitsunobu reaction of the 5-hydroxymethyl derivative (II) with aromatic alcohols or N-nucleophiles. The imidazoline (III) is prepared in 4 steps from 2,3-diaminepropionic acid (I) in excellent overall yield. -(DEFACQZ, N.; TRAN-TRIEU, V.; CORDI, A.; MARCHAND-BRYNAERT*, J.; Tetrahedron Lett. 44 (2003) 51, 9111-9114; Unite Chim. Org. Med., Univ. Cathol. Louvain, B-1348 Louvain-la-Neuve, Belg.; Eng.) -Mais 13-091
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