Background
There is still limited data on severe recurrent pneumonia in children, especially in developing countries as Vietnam. This study was conducted to identify the underlying causes and clinical profile of children with severe recurrent pneumonia admitted to the Pediatric Intensive Care Unit (PICU), National Children's Hospital.
Methods
This was a prospective and descriptive study on 110 children with severe pneumonia admitted to the PICU from November 2019 to August 2020. Data were collected to investigate the clinical profile and underlying diseases.
Results
Severe recurrent pneumonia accounted for 29.4%. Underlying causes were diagnosed in 91.8% of sRP children, in which the most common causes were abnormalities in respiratory, cardiovascular system and immune disorders. 74.5% of sRP children admitted to ICU had been previously intubated or ventilated, 34.5% had shock, 7.3% had multiple organ failure. Recurrent lesions on chest x-ray in the same lobe accounted for 18.2%.
Conclusions
The majority of patients with severe recurrent pneumonia had an underlying disease. Comprehensive management is necessary for severe recurrent pneumonia.
In this paper we study some generalized versions of a recent result due to Covert, Koh, and Pi (2015). More precisely, we prove that if a subset E in a regular variety satisfies |E| ≫ q d−1 2
The study describes underlying causes of children with severe persistent pneumonia (sPP) admitted to the Intensive Care Unit (ICU), Vietnam National Children’s Hospital. In the prospective and descriptive study, all patients classified as sPP (pneumonia persisting for 30 days or more, despite receiving antibiotics for a minimum period of 10 days), admitted to ICU, Vietnam National Children’s Hospital from November 2019 to August 2020 were recruited. Patients were divided into groups based on having a recurrent lesion in the same lobe or lesion in multiple lobes before undergoing several investigational tests to identify the underlying causes. 82 patients with sPP accounted for 21.9% of children admitted to ICU due to pneumonia and 10.6% of total patients at ICU. Underlying causes were diagnosed in 82.9% of sPP children, with the most common causes are abnormalities in respiratory (19.5%), immune disorders (18.3%), congenital heart diseases (17.1%). Underlying causes couldn’t be identified in 17.1% of the patients, among whom necrotizing pneumonia or lung abscess account for 50%, ARDS 21.4%, and tuberculosis 14.3%. Local and recurrent x-ray lesions in one lung lobe accounted for 22%.
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