No abstract

Hepatocytes are highly differentiated cells capable of multiple cycles of proliferation. Recent work with transgenic models indicates that the replicative capacity of nonneoplastic differentiated hepatocytes in vivo far exceeds limits established for fibroblasts in culture.

Abstract. Hepatocyte growth factor (HGF) is a pleiotropic growth factor which, in addition to its mitogenic potency for primary hepatocytes, also has a role in the regulation of cell motility, cell growth and morphogenesis. In the present study, we show that c-met, the high-affinity receptor for HGF, is expressed on human cord blood (