The work is devoted to the investigation of two different methods for
introduction of silicon into ceramics, based on biogenic hydroxyapatite
(BHA), on the structure and properties. Thus, porous samples of Si-modified
BHA-based ceramics containing 2 or 5 wt.% Si were prepared by using two
different precursors, i.e. polymethylsiloxane polyhydrate and fine silica
(Aerosil? 200) powder. After the modification with silicon a marked change in
the structure of material was observed. The use of Aerosil? 200 permits
preparation of a more uniform structure as compared to that obtained by using
polymethylsiloxane polyhydrate. However, the latter promotes an increase in
both the porosity of samples (from 43 to 62.3%) and their solubility in
saline (from 0.18 to 1.20wt.%/day) as compared to the results obtained after
the modification with Aerosil? 200, where maximal porosity and solubility
were 48.5% and 0.23wt.%/day, respectively. At the same time, the modification
of hydroxyapatite ceramics with silicon using silica makes it possible to
prolong release of a drug (e.g. Rifampicin) out of sample pores for the first
24 h as compared to the ceramicsmodified with polymethylsiloxane polyhydrate.
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