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The rate at which two particles separate in turbulent flows is of central importance to predict the inhomogeneities of particle spatial distribution and to characterize mixing. Pair separation is analyzed for the specific case of small, inertial particles in turbulent channel flow to examine the role of mean shear and small-scale turbulent velocity fluctuations. To this aim an Eulerian-Lagrangian approach based on pseudo-spectral direct numerical simulation (DNS) of fully developed gas-solid flow at shear Reynolds number Re τ = 150 is used. Pair separation statistics have been computed for particles with different inertia (and for inertialess tracers) released from different regions of the channel. Results confirm that shear-induced effects predominate when the pair separation distance becomes comparable to the largest scale of the flow. Results also reveal the fundamental role played by particles-turbulence interaction at the small scales in triggering separation during the initial stages of pair dispersion. These findings are discussed examining Lagrangian observables, including the mean square separation, which provide prima facie evidence that pair dispersion in non-homogeneous anisotropic turbulence has a superdiffusive nature and may generate non-Gaussian number density distributions of both particles and tracers. These features appear to persist even when the effects of shear dispersion are filtered out, and exhibit strong dependency on particle inertia. Application of present results is discussed in the context of modelling approaches for particle dispersion in wall-bounded turbulent flows. C 2012 American Institute of Physics. [http://dx

Recent experiments in a turbulent boundary layer by Gerashchenko et al. (J. Fluid Mech., vol. 617, 2008, pp. 255–281) showed that the variance of inertial particle accelerations in the near-wall region increased with increasing particle inertia, contrary to the trend found in homogeneous and isotropic turbulence. This behaviour was attributed to the non-trivial interaction of the inertial particles with both the mean shear and gravity. To investigate this issue, we perform direct numerical simulations of channel flow with suspended inertial particles that are tracked in the Lagrangian frame of reference. Three simulations have been carried out considering (i) fluid particles, (ii) inertial particles with gravity and (iii) inertial particles without gravity. For each set of simulations, three particle response times were examined, corresponding to particle Stokes numbers (in wall units) of 0.9, 1.8 and 11.8. Mean and r.m.s. profiles of particle acceleration computed in the simulation are in qualitative (and in several cases quantitative) agreement with the experimental results, supporting the assumptions made in the simulations. Furthermore, by comparing results from simulations with and without gravity, we are able to isolate and quantify the significant effect of gravitational settling on the phenomenon.

Purpose: Computer simulations of hepatic radio-frequency ablation (RFA) were performed to: (i) determine the dependence of the vessel wall heat transfer coefficient on geometrical parameters; (ii) study the conditions required for the occurrence of the directional effect of blood; and (iii) classify blood vessels according to their effect on the thermal lesion while considering blood coagulation. The information thus obtained supports the development of a multi-scale bio-heat model tailored for more accurate prediction of hepatic RFA outcomes in the vicinity of blood vessels. Materials and methods: The simulation geometry consisted of healthy tissue, tumor tissue, a monopolar RF-needle, and a single cylindrical blood vessel. The geometrical parameters of interest were the RF-needle active length and those describing blood vessel configuration. A simple, novel method to incorporate the effects of blood coagulation into the simulation was developed and tested. Results: A closed form expression giving the dependence of the vessel wall heat transfer coefficient on geometrical parameters was obtained. Directional effects on the thermal lesion were found to occur for blood vessel radii between 0.4 mm and 0.5 mm. Below 0.4 mm blood coagulation blocked the flow. Conclusions: The closed form expression for the heat transfer coefficient can be used in models of RFA to speed up computation. The conditions on vessel radii required for the occurrence of directional effects on the thermal lesion were determined. These conditions allow the classification of blood vessels. Different approximations to the thermal equation can thus be used for these vessel classes.

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