Background: Intraoral scanner (IOS) is a medical device used for capturing direct optical impressions and composed of a handheld camera (hardware), a computer and software. Digital impressions by intraoral scanning have become an increasingly popular alternative to conventional impressions. The aim of this systematic review is to assess the studies regarding the various available technologies for IOS and evaluate the most accurate IOS system for cases with multiple implants and identify the factors that can influence its accuracy. Materials and Methods: A comprehensive electronic search was done in online databases, 'Pubmed', 'Google Scholar' and 'Cochrane' based on pre-determined eligibility criteria. In-vitro studies, In-vivo studies and Randomized controlled trials assessing the accuracy of intra-oral scanner technology were selected after thorough screening. The search strategy covered all studies published until February 2019 and yielded a total of 11 articles out of which 8 studies were determined to fulfil the inclusion criteria and were selected for this review. Data extraction from the included studies was conducted by the primary author and reviewed by the second author. Results: The information collected included sample size and population, study design, intervention, scanning methods, comparisons and outcome measures. 5 out of 8 included studies compared the distance deviation of the acquired scans from the true values while the remaining 3 studies gave trueness and precision values as the outcome variables. A forest plot on scanner precision displayed slightly higher precision levels in the TRIOS scanner compared to the other intraoral scanners. Conclusion: Despite the limitations this study, it can be concluded that active wavefront sampling is more accurate than the other intraoral scanning technology employed by commercial scanners.
Aim: The aim of this systematic review is to analyze the existing evidence on the quality of life of patients completely edentulous in the mandible. Materials and Methods: A search questionnaire was formulated using population intervention comparison outcome (PICO) analysis, and a comprehensive search was initiated in PubMed Central, Medline, Cochrane, and Google Scholar databases for the related topics. Manuscripts published till December 2019 were included in this review. Out of the 63 articles obtained from searching all databases, 27 studies were excluded based on the title and abstract. Out of the remaining 36 studies, 12 were excluded based on the inclusion and exclusion criteria of our interest and 24 were included on the basis of core data. Results: One review author identified randomized trials meeting inclusion criteria for this review. Two review authors extracted data and assessed study quality. The oral health-related quality of life in completely edentulous mandibular patients wearing implant-supported overdentures was better when compared to conventional tissue-supported complete denture, and a minimum two implant-supported mandibular complete denture has sufficient improvement in oral health-related quality of life. Conclusion: There are about more than 170 reviews and clinical trials that have been published in support of the same for the past two decades. Thus, the clinicians may not be tempted in placing additional implants in well-formed mandibular edentulous ridges. To enhance the understanding of mandibular implant overdenture treatment, clinicians must scrutinize the existing evidence and formulate a protocol by striking a balance between efficient and evidence based treatment.
The behaviour of hafnium as surface coating in biological environments has not been studied. Little is known about osseointegration of hafnium-coated titanium implants. Thus, further studies of hafnium coating under biological conditions are required in order to determine the suitability of this material, as a surface coating for biomedical application. The aim of the study is to analyse the difference between hafnium-coated titanium and uncoated titanium by evaluating the osseointegration ability of hafnium metal and mechanism of which promotes better bone integration. The study was conducted with a split mouth design on 16 Wistar Albino rats of both sexes, at the age of 6-7 months, weighing 2526.5 ± 74.4 g . Self-tapping titanium osteosynthesis screws ( 4 mm × 2 mm ) (LeForte System Bone Screw®) were implanted in the mandible of rats: Group A (pure titanium screws, n = 12 ) and Group B (hafnium-coated screws, n = 12 ). The implanted screws’ stability was checked and noted with a specially customised torque apparatus during insertion and removal of implant. The tissue sections were then processed for hematoxylin and eosin and Masson’s trichrome for bone and connective tissue examination, after 4 and 8 weeks of placement. Hafnium coating appears to have offered similar biocompatibility (aspartate transaminase (AST), alanine aminotransferase (ALT), and creatine kinase (CK) enzyme assay), statistically significant improvement (independent Student’s t -test, p < 0.05 ) in insertion torque ( 25.42 ± 3.965 ) and removal torque ( 29.17 ± 2.887 ) than commercially pure titanium with insertion torque ( 22.08 ± .575 ) and removal torque ( 25.42 ± 2.575 ). Hafnium coating in the rat mandible showed promising osseointegration with good tissue biocompatibility. Further human trials of hafnium-coated implants are needed to understand the biological behaviour better to enhance clinical performance.
Chitosan (CTS) is a biocompatible polymer that has been widely researched for tissue engineering purposes. It has demonstrated a significant role in bone tissue engineering in the last two decades. Being a natural polymer obtained from chitin, a major component of crustacean exoskeleton, it has varied uses. Lately, attention has been given to chitosan composite materials due to its minimal foreign body reactions, antibacterial nature, biocompatibility, biodegradability, and the ability to be molded into various shapes and forms. It can be used as porous structures, suitable for cell ingrowth and osteoconduction. The aim of this research was to assess the biocompatibility of a chitosan nanoparticle and hafnium metal-based composite and project its use for bone tissue engineering. In the present study, we have prepared chitosan nanoparticles and their based hafnium composite and it was analyzed for its cytotoxic effect using brine shrimp lethality assay and antimicrobial activity using the disc diffusion method. There was a significant difference between the concentrations used (p<0.01), when One way ANOVA statistical analysis was performed. The current study substantiates the antimicrobial activity and highlights the possible cytotoxicity of the CTS and hafnium composite.
Numerous biomaterials have been constantly researched upon for dental implants. We wanted to evaluate alternative elements that may have the potential to offer equivalent or superior osseointegration. One such element of interest is Hafnium. In the periodic table by IUPAC, tantalum belongs to period 6 (d block) of periodic table. Hafnium belongs to the same period and block as tantalum, in the periodic table. Various in vitro studies were conducted on hafnium metal. Studies have reported that hafnium has a similar response in soft and hard tissues in two different animal species (rat and rabbit), which suggests that hafnium might be an interesting material for biomedical applications. This review aims at analysing the existing literature on hafnium as potential implant biomaterial.
Introduction - Thermoplastic polymers have many potential uses in medicine and dentistry as an alternative to the commonly used titanium. Since the 1980s, polyaryletherketones (PAEKs) have been increasingly employed as biomaterials for trauma, orthopedic, and spinal implants. Due to several advantages of these materials, metal-free restorations are performing an important role in current medical therapies. PEEK is biologically inert and various surface modifications are given to increase its osseointegration potential of PEEK, Acid etching is the most simple and cost effective method of treatment. The aim of this study is to evaluate the surface roughness and wettability of 2 different acid etching techniques of PEEK samples - Magnetic stirring and ultrasonic. Material and methods - PEEK samples thicknesses of 2 mm and diameters of 15 mm was used in the study and the sulfonation procedure was done magnetically and ultrasonically for 6 mins and samples were rinsed with acetone for 10 mins, washed with deionized water for 10 mins and finally dried at 37°C. The results of the study were subjected to statistical analysis in SPSS software version 23.0. Independent t test was performed for the parameters. Results - when comparing 2 groups magnetic stirred sulfonated PEEK (MSPEEK) and Ultrasonic PEEK (USPEEK) results showed statistically significant difference present. (P < 0.05) in surface roughness and in wettability no significant difference is seen (P > 0.05). Conclusion - The literature suggests that PEEK offers an alternative to titanium, especially in cases of orthopedics and trauma. Its properties make it an interesting material in Dental implantology to be performed with CAD-CAM. Further studies are required to obtain sufficient scientific evidence to enable its uses as a permanent material.
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