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Thyroid problems are among the most common endocrine disorders presently seen worldwide. Hypothy-roidism results when the thyroid gland fails to produce enough of the thyroid hormone, due to structural or functional impairment that significantly impairs its output of hormones, this leads to the hypo metabolic state of hypothyroidism. According to Charaka presentation of multiple Granthi around the neck is called Gandmala and single swelling on the Parshava of the neck is Galganda. So Galganda can be co-related with hypothyroidism. The root cause of hypothyroidism is disequilibrium of tridosha. This is an effort to find out better treatment of Galagand by successfully treated case of Galagand with help of hypothetical herbomineral compound.