Theoretical investigation of a short electron beam (extended bunch) interaction with a backward wave propagating in a slow wave structure demonstrates the possibility of producing ultrashort superradiance pulses with a peak power which exceeds the power of the driving beam (conversion factor K>1). It is shown that a nonuniform slow wave structure with optimized profile is beneficial in order to increase the conversion factor. The results of theoretical analysis are confirmed by the experiments. At X band using the SINUS-150 accelerator (4 ns, 330 kV, 2.6 kA) 0.6-0.8 ns superradiance pulses with a peak power of 1.2 GW and a conversion factor of 1.5 were obtained. Similar experiments at Ka-band based on the RADAN-303 accelerator (1 ns, 290 kV, 2.5 kA) demonstrated production of the superradiance (SR) pulse with duration 200 ps and peak power about 1 GW (conversion factor of 1.4).
This article presents results of theoretical and experimental studies on the production of ultrashort~a few RF cycles duration! microwave pulses of gigawatt peak powers based on superradiance from high-current electron beams. With the Cherenkov backward-wave-electron-beam interaction in a low-dispersion slow-wave structure, microwave pulses with a peak power greater than the peak power of the driving electron beam have been produced for the first time. In an experiment using the SINUS-150 compact high-current electron accelerator, with a 2.6-kA injected beam current and a 330-kV electron energy, microwave pulses of 1.2 GW peak power and ;0.5 ns duration~FWHM! were generated in the X-band. Production of superradiance pulses in a repetitive regime~3500 Hz! in the Ka-band has been demonstrated using a compact hybrid SOS-modulator. The effect of spatial accumulation of microwave energy in extended slow-wave structures with substantially nonuniform coupling has been demonstrated. In an experiment using the SINUS-200 compact accelerator, X-band pulses of ;3 GW peak power and 0.6-0.7 ns width~FWHM! were produced with a power conversion efficiency of 150-180% and an energy efficiency of ;15%.Calculations performed with various D J values have shown the following: With any value of j k . . 1, the optimum value of D J must be such~D J opt ; exp~Ϫj k !! that the region where the amplitude of the RF current saturates due to the non-188 A. A. Eltchaninov et al.
This study was undertaken to examine ultrasound (US) mechanisms and their impact on chemical and biological effects in vitro as a function of changing pulse repetition frequency (PRF) from 0.5 to 100Hz using a 1MHz-generator at low-intensities and 50% duty factor (DF). The presence of inertial cavitation was detected by electron paramagnetic resonance (EPR) spin-trapping of hydroxyl radicals resulting from sonolysis of water. Non-cavitational effects were evaluated by studying the extent of sucrose hydrolysis measured by UV spectrophotometry. Biological effects were assessed by measuring the extent of cell killing and apoptosis induction in U937 cells using Trypan blue dye exclusion test and flow cytometry, respectively. The results indicate significant PRF dependence with respect to hydroxyl radical formation, cell killing and apoptosis induction. The lowest free radical formation and cell killing and the highest cell viability were found at 5Hz (100ms pulse duration). On the other hand, no correlation was found between sucrose hydrolysis and PRF. To our knowledge, this is the first report to be devoted to study the impact of low PRFs at low-intensities on US-induced chemical and biological effects and the mechanisms involved. This study has introduced the role of "US streaming" (convection); a forgotten factor in optimization studies, and explored its importance in comparison to standing waves.
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