Abstract. Cementoma is a very rare odontogenic neoplasm of mesenchymal origin. Clinically, in 3 horses, multiple bony enlargements of the upper and lower jaw extending into the oral cavity were observed. Radiographically, multiple, well-circumscribed, radiopaque masses surrounding the roots of the upper and lower incisors or an upper premolar tooth were present. Due to malocclusion and local pain, single teeth were extracted in each case. Grossly, a hard grayish-white mass surrounding the root of the incisors and the premolars was identified. Histopathologically, the tumors consisted of excessive deposition of cementum-like tissue. Cells, resembling cementoblasts, lined irregularly shaped lacunae, which were present in the tumor tissue, and showed minimal cellular pleomorphism. Mitotic figures were not present. Macroscopically and histologically, all 3 equine cases displayed great similarities to cementomas in other species. However, due to their high degree of differentiation, hypercementosis must be considered as a differential diagnosis.
ObjectiveTo compare attempts to stand, duration, quality, and occurrence of injuries between head‐tail rope assistance and unassisted recoveries in healthy horses undergoing general anesthesia for elective surgeries.Study designRandomized, prospective, clinical trial.MethodsThree hundred one healthy horses undergoing elective surgeries were randomly assigned to recover with head‐tail rope assistance (group A) or unassisted (group U); 305 recoveries (group A, n = 154; group U, n = 151) were analyzed. Anesthesia was maintained with isoflurane and triple drip. For each recovery, attempts to stand, duration, quality, and recovery‐associated injuries were recorded. Data were analyzed by linear regression and analysis of covariance.ResultsAnesthesia duration was similar between groups (mean ± SD, 70 ± 29 minutes). Compared with group U, group A had fewer attempts to stand (median [range], group A = 1 [1‐7] vs group U = 3 [1‐34]) and shorter duration of recovery (mean ± SD, A = 36 ± 12 minutes vs U = 41 ± 15 minutes). Recovery quality in group A (28 points [15‐70]) was better than that in group U (38 points [11‐87]). More horses had recovery‐associated injuries in group U (9 horses) compared with group A (2 horses). One horse per group was euthanized.ConclusionHead‐tail rope assistance reduced standing attempts, shortened recovery duration, improved recovery quality, and reduced recovery‐associated minor injuries after general anesthesia for elective surgery in healthy horses. Fatalities could not be prevented.Clinical significanceHead‐tail rope assistance may improve recovery in healthy horses after short‐duration elective surgeries with isoflurane and triple drip.
A kinetic study of lung DNA-synthesis during simulated chronic high-altitude hypoxia. Rats were exposed to chronic hypobaric hypoxia at a simulated altitude of 4250 m for 3, 6, 9, 12, 20, and 35 al., 1963;Burton et al., 1967;Barer et al., 1970; Abrahams et al., 1971;McMurtry et al., 1973). The pulmonary hypertension is the result of a fixed increase in pulmonary vascular resistance due to structural changes in the pulmonary blood vessels that occur in the course of long-term hypoxia.Although the histological changes are well documented by Arias-Stella and Saldafia (1962) and by Heath (1959), it is not clear whether they are hypertrophic or hyperplastic, and we are also ignorant of the time course of these changes. In order to investigate the mechanism involved and to monitor the onset and the kinetics of the expected cellular proliferation the present cytokinetic study of pulmonary response to chronic hypoxia was designed. MethodsThirty female Wistar rats weighing 220-250 g were used for the experiments. They were randomly divided into groups of three: six groups were kept in a decompression chamber for 3, 6, 9, 12, 20, and 35 days respectively and were exposed to a simulated altitude of 4250 m. Three groups were taken as controls at the beginning of the 'Supported by the Deutsche Forschungsgemeinschaft grant No. Si 207/2 study and on day 3, 12, and 35 respectively. The animals were exposed to hypoxia for 22 hours daily and they were allowed access to food and water. After anaesthesia with 2 mg/kg pentobarbital sodium (Nembutal') a medium thoracotomy was performed, and the middle lobe of the right lung was excised and cut into slices. Two hundred milligram portions of each lung were immediately incubated in 3 ml Krebs-Ringer medium containing 20 ,tCi of 3H-thymidine (H3-thymidine, 24 6 Ci/mmol, Amersham-Buchler, Braunschweig) at 35°C for 60 minutes. The incubation was stopped by the addition of 5 ml icecold 3N TCA. The slices were homogenised in 10 ml 5% TCA (w/w) and centrifuged at 3000 g for 5 minutes. The DNA of the sediment was hydrolysed in 5 ml 5% TCA at 95°C for 30 minutes. The insoluble material was removed by centrifugation. One hundred microlitre samples of the supernatant were measured in duplicate for both radioactivity and DNA (Burton, 1968). The DNA synthesis rate was expressed as specific radioactivity (cpm/,tg DNA). Liver slices in portions of approximately 300 mg were run as controls. ResultsRats that were exposed to chronic hypobaric hypoxia (440 Torr) for a variable period of time (3-35 days) increased their lung DNA synthesis considerably. Figure 1 shows a rapid and continu-578 on 7 May 2018 by guest. Protected by copyright.
After inhalation of leather-impregnation sprays in a confined space five patients developed acute and severe symptoms of alveolitis, with disorders of ventilation and diffusion as well as marked radiological changes. In one case without any treatment pulmonary fibrosis developed. In the other four immediate administrations of steroids produced complete healing. Inhalation of small amounts of leather-impregnation spray produced no changes in pulmonary function tests in volunteers. There were no similarities with forms of alveolitis produced by other noxious inhalation agents.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.