The mechanism of action of X-ray irradiation on the course of certain skin diseases, especially those whose etiology is unknown, is not yet entirely clear. There is no doubt that the autonomic nervous system, functionally and anatomically connected both with the central nervous system and with all organs and tissues, and in particular with the skin (its vessels, sweat and sebaceous glands), has an effect on all functions of the skin, its trophism and course inflammatory processes. Although the details of this effect on the inflammatory process have not been clarified and are still very contradictory, nevertheless a number of experimental works of old and recent times indicate an intimate dependence of the inflammatory process in the skin on the nervous system (Spiess, Thomas, Luvis, Speransky, Greenstein, Alperin and others).