Aims/hypothesis GFR is commonly estimated using the four-variable Modification of Diet in Renal Disease (MDRD) formula and this forms the basis for classification of chronic kidney disease (CKD). We investigated the effect of obesity on the estimation of glomerular filtration rate in type 2 diabetic participants with CKD.
Diabetes is a complex endocrine disease that affects more than 100 million of people worldwide (6% of the total population). The prevalence of Diabetes mellitus is increasing, despite multiple treatment options. Along with allopathic medications, several formulations or single forms of plant origin are employed in its treatment, especially in non-insulin dependent diabetic mellitus (NIDDM). Herbal medications are effective, broad range of action, fewer adverse effects, and are relatively inexpensive, making them a suitable alternative. The aim of this study is to investigate hypoglycaemic effect of Sariva (Hemidesmus indicus R.Br.) root phanta (teabag) in Madhumehi. The current trial is a randomised, parallel group interventional trial. After initial screening for inclusion criteria, 60 patients were enrolled and separated into 3 groups (20 patients each), which was conducted according to the International Conference on Harmonization-Good Clinical Practices Principles (ICH-GCP) or the Declaration of Helsinki guidelines and statistically analysed using the chi square test. Madhumeha had a better clinical outcome with the medication. The majority of vata-kaphaja prakriti had side effects such as constipation and nausea. Patients in the 40–50-year age group with Vataja-dosha derangement were found to be more prone to DM-2. In married mostly in males, there is a greater preponderance. Madhura, snigdha guṇa relieves vata, Tikta rasa relieves kapha, meda duṣya, sheeta virya relieves pitta; Hence it has tridoṣatmaka activity, which is beneficial in the treatment of Madhumeha. Sariva in the form of teabag has kaphaghna, vataghna, kandhughna (curing pruritus), meha durgandhi nashan, sarvamehahara properties. Thus, it collectively acts in Madhumeha.
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