Summary: Epidemiological studies indicate a high prevalence of vitamin D deficiency among children and adult population in different countries [1][2][3][4][5][6][7][8]10]. In connection with the numerous studies of foreign authors, which proved the adverse effects on the body vitamin D: the development of autoimmune and inflammatory disorders, cancer (mammary, pancreas, prostate gland, intestine and colon), heart failure, hypertension, myocardial infarction, diabetes mellitus, obesity. In connection with the urgency of the problem of insufficient content of cholecalciferol in the blood of children, a survey of 229 children of different ages. This study is a fragment of a multicenter, prospective, cohort, pharmacoepidemiological studies assessing the provision of child population younger age group vitamin D in the Russian Federation "SPRING". The results of study of vitamin D metabolites in serum of healthy children from 3 to 6 years, adolescents aged 15-17 years living on the territory of Amur region. These results allow to speak about necessity of revision of existing methodological recommendations taking into account modern approaches to the prevention and treatment of deficiency with different degrees of severity of vitamin D in children and adolescents.
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