A rare case of split cord malformation with neurenteric cyst is presented. The clinical, radiological and surgical findings are presented, and the possible embryological basis is discussed. To our knowledge, only seven such cases have been reported in the literature.
Introduction Oral dysplasia is a frequent precancerous condition that may lead to oral cancer. The histopathologic abnormalities exhibited in a chronic, progressive, and premalignant condition of the oral mucosa are referred to as oral epithelial dysplasia (OED). It might show up as erythroplakia, leukoplakia, or leukoerythroplakia. OED is a premalignancy histologic marker that predicts a higher likelihood of squamous cell carcinoma development. Aims and objectives The aim of this study is to identify an association between Ki-67 protein expression and histological grading of OED and oral squamous cell carcinoma (OSCC) and to compare the expression of Ki-67 in different grades of OED and OSCC with the prognosis. Materials and methods The current retrospective research is focused on evaluating epithelial dysplasia and analyzing the function of Ki-67 as a prognostic marker after receiving institutional ethical approval. Group I - normal oral mucosa (NOM), Group II - OED, and Group III - OSCC were included in the study. For statistical analysis, SPSS Statistics version 21.0 (IBM Corp. Released 2021. IBM SPSS Statistics for Windows, Version 28.0. Armonk, NY: IBM Corp) was utilized. The Cox regression model was employed to look at interactions between various prognostic variables. At p<0.05, differences were deemed statistically significant. Results Ki-67 expression was confined to the basal layers in the normal oral epithelium and in the basal, suprabasal, and spinous layers in OED. Ki-67 positive cells were mostly found on the perimeter of well, moderate, and poorly differentiated OSCC tumor nests with Ki-67 positive cells scattered throughout OSCC. According to statistical analysis, there is a substantial difference in expression between OED and NOM, OSCC and NOM, and OED and OSCC. Conclusion Our study showed that there is a progressive increase in Ki-67 expression across various grades of OED, and the highest expression was noted in OSCC. Early identification and prompt treatment will help in improving the quality of life of such patients.
<p class="abstract"><strong>Background:</strong> The reported incidence of obstetric brachial plexus palsy (OBPP) varies from 0.3 to 2.5 per 1000 live births<strong></strong>resulting in internal rotation deformity and weak abduction of the involved side shoulder<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> To retrospectively analyse the functional results of the Sever- L‘ Episcopo procedure for OBPP with a minimum follow-up of 2 years to a maximum of 13 years using modified Mallet scoring system for shoulder.<strong></strong></p><p class="abstract"><strong>Results:</strong> A significant improvement in the range of abduction and the restoration of external rotation of shoulder was achieved with Sever- L’Episcopo procedure<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> The results of secondary reconstruction of a dysfunctional shoulder by means of a Lattismus dorsi & Teres major transfer as described by Sever- L’Episcopo is definitely beneficial. However this procedure will improve, but will not normalize, function. Apart from functional improvement this procedure corrects a deformity thereby easing the psycho-social stigma associated with it<span lang="EN-IN">.</span></p>
Scapholunate dissociation is the most common carpal instability. We are presenting an interesting case of a 24yr old male with scapholunate instability following trauma. Appropriate investigations were done and surgical intervention was done on the same day. The ruptured ligaments were repaired and bony components scapholunate and scaphocapitate were corrected and fixed. Patient was immobilized in plaster for 8 weeks following which active mobilization exercises were started. The functional results were excellent and we have reported them using the mayo wrist score.
<p class="abstract"><strong>Background:</strong> Fingertip injuries are common due to industrial accidents, ranging from small laceration and nail bed injuries to traumatic amputation and severe crush. It is best retain as much native tissue when viable. Surgical options in treating the fingertip injuries are individualized to each patient considering the injury pattern, age, hand dominance and occupation<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> It is a retrospective study of 102 fingertip injuries in 95 patients, whose age ranges from 2 years to 60 years over a period of 3 years.<strong></strong></p><p class="abstract"><strong>Results:</strong> In 90% of patient’s primary wound healing was achieved in 2 weeks period. All were satisfied with the functional outcome and average period of returning to the work is 4 weeks<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Fingertip injuries needs individualized management specialized to achieve optimum results, maximum patient satisfaction rates and early return to pre injury occupation level<span lang="EN-IN">.</span></p>
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