Abstract. In the course of this research work woven synthetic prosthesis reinforced with natural silk yarns was designed and manufactured. Biomechanical properties of surgical natural silk were studied during designing of the structure of the walls of the prosthesis. The experiment gave good data of elasticity and strain properties in a process of laboratory testing of samples of natural fibers. The previous practical experience was also used, for example, various vascular prostheses made from polyurethane complex yarns and polyester monofilaments. As a result, the authors of the scientific work proposed a combined wall structure of vascular prosthesis, consisting of polyester, polyurethane, and natural silk surgical yarns. After the implantation of the synthetic prosthesis reinforced with natural silk yarns, these natural silk yarns completely dissolve in the body for several years. Living tissue is gradually growing into the walls of synthetic prosthesis, replacing dissolved natural silk yarns. Experimental tests confirmed that a modulus of elasticity of innovative prosthesis is close to modulus of elasticity of natural blood vessels. The innovative structure of blood vessel prosthesis combined with such parameters can provide a long-term normal hemodynamics.
− Woven synthetic vascular prosthesis consisting of polyester yarn, nanostructured particles of colloidal silver and polyurethane yarns and natural silk surgical thread were offered in the process of this scientific and practical activity. Previous scientific and practical experience of manufacturing various types of vascular prostheses was used in designing a new prosthesis. Advanced biomechanical and other properties used in the development of yarns were examined. The innovative structure of woven walls of prosthesis has normal biomechanical properties. Expressed antimicrobial activity of nanostructured wall of the prosthesis is an important indicator for the successful incorporation of synthetic implant in a living organism. These prostheses are capable of providing long-term normal physiologic hemodynamics in the recycled circulatory system. Keywords − Silver nanostructured yarn, synthetic vascular implant, woven synthetic vascular prosthesis.
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