Mastitis is the most common disease for cattle, causing great economic losses for the global dairy industry. Recent studies indicate the multi-agent and microbiome diversity of this disease. To understand the nature of mastitis and investigate the role of the microbiome in the development of pathologies in the udder of bovines, we performed NGS sequencing of the 16S rRNA gene of cow’s milk with pathologies of the udder. The obtained data show a significant increase in the Cutibacterium, Blautia, Clostridium sensu stricto 2, Staphylococcus, Streptococcus and Microbacterium genera for groups of cows with udder pathologies. Increasing relative abundance of the Staphylococcus and Streptococcus genera was associated with subclinical mastitis. Our data show that a relative increase in abundance of the Staphylococcus and Microbacterium genera may be an early sign of infection. We have shown, for the first time, an increase in the Colidextribacter, Paeniclostridium and Turicibacter genera in groups of cows with mastitis. These results expand our understanding of the role of the microbiome in the development of bovine mastitis.
The article presents the results of studies on the efficacy of the preparation «AMM» for the prevention of mastitis in cows in the early postpartum period, its effect on the morphological and immunological blood parameters.
The article presents the results of the effect of proautovak on the morphological and biochemical blood indicators of cows. The prophylactic effect of the application of this drug has been noted, which is expressed in a decrease in the intensity of lipid and protein peroxidation processes, endogenous intoxication phenomena while increasing local protection factors, activating an antioxidant system, which clinically manifested itself by a decrease in the incidence of mastitis in cows in the postpartum period.
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