Protoplasmic streaming in plant cells is directly visible in the cases of Chara corallina and Nitella flexilis, and this streaming is understood to play a role in the transport of biological materials. For this reason, related studies have focused on molecular transportation from a fluid mechanics viewpoint. However, the experimentally observed distribution of the velocity along the flow direction x, which exhibits two peaks at Vx = 0 and at a finite Vx(≠0), remains to be studied. In this paper, we numerically study whether this behavior of the flow field can be simulated by a 2D stochastic Navier-Stokes (NS) equation for Couette flow in which a random Brownian force is assumed. We present the first numerical evidence that these peaks are reproduced by the stochastic NS equation, which implies that the Brownian motion of the fluid particles plays an essential role in the emergence of these peaks in the velocity distribution. We also find that the position of the peak at Vx(≠0) moves with the variation in the strength D of the random Brownian force, which also changes depending on physical parameters such as the kinematic viscosity, boundary velocity, and diameter of the plant cells.

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Context: Previously, we investigated the relationship between the nature of the substituent at the 5-position of the uracil ring and the action of the corresponding uracil derivatives on immortalized lung cells. In the present study, we analyzed the impact of some 6-substituted uracil-derivatives on the regeneration potential of the lung cells (LC). Aims: To evaluate uracil derivatives capable of stimulating lung cell proliferation to create drugs that accelerate lung regeneration. Methods: The level of cell proliferation, maximum tolerated dose, and toxic effect of 6-substituted uracil derivatives (9 compounds) were studied on the immortalized lung epithelial cells and compared with the known drug 6-methyluracil. Results: The maximum tolerated dose of compounds for the LC line depends on the chemical structure of the compounds. The highest level of cell proliferation and tolerated was demonstrated when was used 3-methyl-6-cyclopropyluracil and 1-butyl-6-methyluracil. Conclusions: 3-methyl-6-cyclopropyluracil and 1-butyl-6-methyluracil exhibit a high proliferative activity in vitro so they could be recommended for additional studies of regenerative activity in vivo.

Skyrmion is a topologically stable spin texture and expected to be applied to the future computer memory. On the semiconductors such as FeGe and MnSi, the skyrmion configuration is stable in the sense that it is not strongly affected by a small variation of external stimuli such as temperature, magnetic field etc. In recent experiments, it was reported that the skymion shape is deformed from isotropic (or circular shape) to anisotropic (or elliptic shape) by an external mechanical stress. This shape deformation is caused by the so-called “strain-induced anisotropy (SIA)” of Dzyaloshinskii-Moriya interaction (DMI). In this presentation, we study the reason why this SIA appears in the DMI coefficient on the basis of Finsler geometry modeling technique by introducing a microscopic strain field τ, which is caused by or interacts with the applied external mechanical force.