Objectives: To assess extent of recognition of major fetal heart structures by transabdominal high frequency probe in first trimester in routine clinical work. Methods: From January 2011 to June 2011, 242 women had 11-14 week scan by two FMF certified operators. Examination of fetal morphology, including heart, as well as chromosomal abnormalities screening was done in allocated period of 30 min. We checked if it is possible to see 4-chamber view, AV valves, ventricles, left and right outflow tract, three vessel view, aortic arch and VCI in different gestations (55)(56)(57)(58)(59)(60)(61)(62)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)(77)(78)(79)(80). All scans were done transabdominally, with a high frequency probe, cardiac setting (Accuvix, Medison), and no colour Doppler was applied. Results: When CRL was 45-54 mm, 4cv was seen in 60% of cases, while 3vv in 2%. Starting from CRL 65 mm, 4cv was seen in all cases, whereas 3vv was seen in one third (table 1). All scans were done within allocated 30 min. BMI influenced visibility when structures were not easy to be seen (e.g. in CRL 45-54 mm group mean BMI when ventricles are seen was 22.8, when not 28.6 (P = 0.039). When the structures were difficult to be seen, even in late first trimester, BMI did not make a difference (in 75-84 mm group mean BMI when 3vv was seen was 22.5, when not 22.7 (P = 0.901). Conclusions: Major cardiac structures can be seen in first trimester with different rate of success, depending on gestation and it is possible to do it without extending the usual duration of scan. Four chamber view is the first to be reliably seen, whereas examination of great arteries during this period remains challenging. Expert system (GE). All cases were first examined with conventional 2D ultrasound for assessment of the type and prognostic appearance of the abnormality. In addition, in each case STIC was performed and several volumes of the region of interest were acquired. The clinical relevance of each volume data set was analyzed.Results: Thirty-three cases of fetal cardiac abnormalities were included in the study period. There were 4 cases with ventricular septal defects, 4 -hypoplastic left heart, 2 -hypoplastic right heart, 1 -isolated aortic stenosis, 1 -monoventricle, 1 -isolated pulmonic stenosis, 2 -rhabdomyoma, 6 -atrioventricular septal defect, 4 -tetralogy of Fallot, 3 -TGA, 2 -DORV and 3 cases with right aortic arch. In most cases STIC contributed significantly with additional information in delineating the type and severity of the defect, although it was only secondary for establishment of the correct diagnosis. Conclusions: STIC provides excellent visualization of the fetal heart and has the potential to improve the detection rate of structural fetal cardiac abnormalities. Pentalogy of Cantrell (PC) is a rare congenital syndrome involving the abdominal wall, the lower sternum, diaphragm, pericardium and heart. The literature contains only few reports of prenatal diagnosis of PC. We present a rare case of PC with partial ectopi...