1,4‐μ‐Glucan synthase activity, but not 1,3‐μ‐glucan‐synthase activity, from Saprolegnia monoica was stimulated by cyclic‐diguanylic acid, an immediate activator of Acetobacter xylinum‐ cellulose synthase. This activator, which increased the Vmax without modifying the Km for UDP‐glucose, was active on solubilized and partially purified enzymes. These results suggest that the fungal system shares a common regulatory mechanism with the bacterial system.
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