V. G. Kvachev scite author profile

ChemInform Abstract The benzimidazoles (I) are coupled with the glycerol chlorohydrin diacetate (II) to give the N-alkylated derivatives (III) which are deprotected, producing the acyclic nucleosides (IV). The related nucleoside analogs (VII) and (VIII) are prepared from (I) via silylation, tin(IV) chloride-mediated coupling with the corresponding acetates, and deprotection. The compounds synthesized have no antiviral activity. The trifluoromethylthio derivatives are cytotoxic.

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V. G. Kvachev

Changes in function and kinetics of macrophages and lymphocytes caused by retinoic acid

Acyclic analogs of nucleosides. Synthesis of hydroxyalkyl derivatives of 2-trifluoromethyl- and 2-trifluoromethylthiobenzimidazole

Retinoic acid modified cell culture for reproducing enteropathogenic viruses

ChemInform Abstract: Acyclic Analogs of Nucleosides. Synthesis of Hydroxyalkyl Derivatives of 2‐Trifluoromethylbenzimidazole and 2‐Trifluoromethylthiobenzimidazole.

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