Findings undoubtedly establish the drug-like effect of nondrug formulation (cosmetic formulation). The use of this formulation may minimize the relative dependency of many steroids and other medicament. As the formulation contains only proven cosmetic ingredients and herbs, long-term use is unlikely to produce any side effects.
JRK's Anti-coff was evaluated for blood purification benefit by phagocytosis. and surprisingly we found that Aniscochilus carnosus showed mucoconstriction benefit, while Ocimum sanctum and Adathoda vasica showed mucolytic property. The clinical implication of the above therapeutic benefits is discussed in detail in the article from the context of Siddha system of medicine. The findings are discussed in the article.
Immune boosting cum wellness benefits of five proprietary siddha drugs such as Aforte, Pesin, Bekay, Caratole and Hista Block tablets were studied. All the above drugs increased the population abundance of Lactobacillus acidophilus. In vitro suggest the possibility of facilitating the probiotic environment in the gut and associated pharmaceutical benefits of probiotics. There is a dip in the population abundance of probiotics is known in several auto immune diseases such as Psoriasis, Vitiligo etc. All the above drug tested were indicated for vitiligo, psoriasis and other auto immune diseases. The new therapeutic benefit of the above drugs along with scientifically proven benefits suggest that these drugs besides having pharmaceutical benefits also may help in auto correction of the system (Tridosha) thereby help to achieve wellness as well besides treatment. This is the first finding on the possible mechanism action of siddha drugs in achieving wellness and details are presented in the paper.
The present study deals with the importance of herbal particle size in the AYUSH oil preparations for psoriasis in order to achieve greater absorption and therapeutic value. More often the viscosity of the oil, deep colour and the density of herbal constituents are associated with superior therapeutic value. But our study has clearly demonstrated that the dermal absorbable herbal constituents (under 40 µm) was less than 10% in most of the Wrightia tinctoria based AYUSH oil preparations sold for the treatment of psoriasis in India whereas Dr. JRK’s 777 oil contain more than 60% of the herbal constituents below 40 µm size. Further the role of particle size besides dermal absorption; in the therapeutic value also established by oxygen species scavenging assay. Findings reveal that smaller the particles greater was the antioxidant effect and hence such herbal constituents not only would offer superior therapeutic effect but also protection to the oil from going rancid. Details are presented in the paper.
Keywords: AYUSH oils, Herbal oil, Psoriasis, dermal absorption, Wrightia tinctoria, rancid oil
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.