Background: The specific dermatoses of pregnanc represent a heterogenous group of ill-defined pruritic skin diseases related specifically to pregnancy and/or the immediate postpartum period. The objective of the study is to determine the patterns of specific dermatoses of pregnancy in a tertiary care hospital. Methods: A total of 450 pregnant females, irrespective of their parity and gestational age were screened for various pruritic skin conditions and those with specific pregnancy dermatoses were identified and evaluated. Results: The age of the study population ranged from 18 to 36 years (mean age 24 years). The study population included 261 (58%) primigravidae and 189 (42%) multigravidae. Seventeen (3.77%) pregnant females had specific dermatoses of pregnancy. Out of these, 9 (52.94%) had pruritic urticarial papules and plaques of pregnancy (PUPPP), followed by pruritic folliculitis of pregnancy in 5 (29.41%), pruritic gravidarum in 2 (11.76%) and pemphigoid gestationis in 1 (5.88%). PUPPP was the commonest specific dermatoses noted in our study. Conclusions: The present study highlights the pattern of specific dermatoses of pregnancy in our hospital. Early diagnosis of specific dermatoses of pregnancy may prevent harmful effect on mother and fetus. The pruritic eruptions of pregnancy, which are not a rare entity can be a source of significant distress to the pregnant female and need timely therapeutic intervention.
Onychomycosis is a common fungal infection of nail plate caused by dermatophytes, non dermatophyte molds & yeasts. Tinea unguium on the other hand refers specifically to infection caused by dermatophytes. Onychomycosis represents 50% of all nail disorders and 30% of all mycotic infections of skin.1 It is distributed worldwide with prevalence of 3% to 9%. It is generally considered as a disease of middle aged and elderly affecting a large and significant number of people. There has been a recent increase in the incidence as well as a spectrum of causative pathogens associated with onychomycosis. 50 patients of onychomycosis who attended our outpatient department were randomly selected. These 50 patients were equally divided into two groups A and B. Patients in group A (25) were given only oral terbinafine 250mg/once daily for 12 weeks. Patients in group B (25) were given oral terbinafine 250mg/once daily for 12 weeks along with 8% Ciclopirox Olamine nail lacquer which is applied topically once daily at night. In our present study combination therapy give high mycological cure rates than oral terbinafine monotherapy. Combination therapy (oral terbinafine 250mg daily dose with 8% ciclopirox olamine nail lacquer) showed 70 % clinical cure rate and 60 % mycological cure.
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