Synthesis and Antimicrobial Properties of Hydrazides of Pyrazol-4-carboxylic Acids and N-(4-Pyrazolyl)hydrazones of Aromatic and Hetaromatic Aldehydes.-All the compounds synthesized (IV) show antimicrobial activity. -(CHORNOUS, V. A.; BRATENKO, M. K.; VOVK, M. V.; SIDORCHUK, I. I.; Khim.-Farm. Zh. 35 (2001) 4, 26-28; Bukovinskaya gos. med. akad., Chernovtsy, Ukraine; RU)
Cyclocondesation of 3-aryl(heteryl)pyrazole-4-carbaldehydes with ethyl acetoacetate and urea (thiourea) in the presence of FeCl 3 · 6 H 2 O afforded 3-aryl(heteryl)-4-(4-pyrazolyl)-1,2,3,4-tetrahydropyrimidin-2-ones(thiones).Scheme 1.
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