Candle nut (Aleuritas molucana) is a plant that can produce oil to stimulate hair growth because it contains oleic acid which is an antioxidant. One core of candle nut seeds can contain as much as 50-60% oil, which can be made into hair care cosmetics through the preparation of hair tonic nanoemulsion. This study aimed to determine the effect of different concentrations of candle nut oil (5%, 6%, and 7%) on the characteristics and stability of a candle nut oil nanoemulsion hair tonic preparation. Candle nut oil was formulated into hair tonic nanoemulsion preparations and then tested for characteristics and stability for cycling test preparations. It was found that there were differences in the characteristics and stability values of formulas I, II, and III. The variations in the concentration of the active ingredient of candle nut oil (5%, 6%, 7%) affected the characteristics of the hair tonic by affecting the droplet size, polydispersity index, zeta potential, pH and viscosity of the preparation. The stability test using the cycling showed that the stability of the hair tonic was affected through changes in the pH value and viscosity of the preparation. Keywords: candle nut oil, characteristics and stability, hair tonic, nanoemulsion
Hair loss is one of the most common hair problems, which usually happens at about 100 strands every day. It has been shown that candlenut oil can help to overcome the problem of hair loss. This study aimed to determine the effect of a hair tonic nanoemulsion in varying concentrations of candlenut oil on accelerating hair growth in Mus musculus. A nanoemulsion hair tonic was created because doing so can increase the solubilization of the oil. In the nanoemulsion form, the penetration of the medicinal ingredients into the skin is accelerated. In this study, nanoemulsions were produced with 5%, 6%, and 7% candlenut oil as formula 1, formula 2, and formula 3. A base without candlenut oil was used as a negative control, and a ginseng hair tonic obtained from the market was used as a positive control. The researchers conducted the hair tonic test by measuring the hair growth and hair density of the Mus musculus at 21 days. The hair growth was -0.442 mm for the negative control; 2.255 mm for the positive control; 1.352 mm for formula 1; 1.773 mm for formula 2; and 3.649 mm for formula 3. The hair weight was 3.20 mg for the negative control; 2.22 mg for the positive control; 2.26 mg for formula 1; 4.54 mg for formula 2; and 6.70 mg for formula 3. This study therefore demonstrated that hair tonic nanoemulsion of candlenut oil can accelerate hair growth. Keywords: candlenut oil, hair growth, hair tonic nanoemulsion
The terpinene-4-ol contained in tea tree oil has broad-spectrum antimicrobial activity. Lavender oil contains linalool which also has antibacterial properties. So, they can be anti-acne. Both oils are formulated as emulgel hand sanitizers because this form has a better-controlled drug release effect and stability. The emulgel contained tea tree oil at 5% combined with lavender oil at 0.5%, 1%, and 2%. The evaluation consisted of physical and chemical characteristics, irritation, and antibacterial activity on skin bacteria. The results showed that each organoleptic formula had white color and a distinctive aroma of both essential oils. The texture was soft, homogeneous, and oil-in-water emulsion type; the viscosity and pH were within the specification range. All the formulas met the dispersion requirements. For the irritation test result using HET CAM methods, the preparation caused mild irritation, and the value of the irritating score increased when lavender oil levels increased. In the antibacterial test for Cutibacterium acnes, the addition of lavender oil intensified the antibacterial activity of tea tree oil. On the other hand, an antibacterial test for Staphylococcus aureus and Staphylococcus epidermis of lavender oil added to tea tree oil does not influence the antibacterial activity of tea tree oil in emulgel preparation. Keywords: emulgel of combination tea tree oil and lavender oil, characteristic, irritation effect, antibacterial property
Argan oil is not only used in facial treatments but can also be used for hair care. Argan oil has hair growth activity as it contains oleic acid and linoleic acid, which act to prevent hair loss, strengthen hair, and protect against harmful hair cosmetics, as well as containing tocopherol, which has antioxidant properties. Tocopherol can help to protect from the effects of UV radiation which can damage hair through the melanin pigment and protein fraction. This study aimed to determine the effect of variations in the concentration of argan oil (Argania spinosa Skeels) with levels of 1%, 2%, 3%, in hair tonic nanoemulsion preparations on the hair growth of mice. Hair growth activity was carried out using mice for 21 days. The data were analyzed using one way ANOVA and paired-sample t test. The results showed that after 21 days of testing, there was an increase in hair growth from each formula and the positive control, of 1.891 mm, 2.33mm, 3.484 mm and 2.225 mm, respectively. The hair weights of formula 1, 2, 3, and the positive control were 0.0028, 0.0059, 0.0111 and 0.0070, respectively. The negative control led to a decrease in length and weight by 0.641 mm and -0.0023, respectively. In conclusion, the preparations of hair tonic nanoemulsion using argan oil at concentrations of 1%, 2%, and 3% promoted hair growth in mice. Keywords: argan oil, hair tonic, nanoemulsion, hair growth activity test, mice
Lipase (triasilglycerol acylhydrolase, E.C, 3.1.1.3) is an enzyme can hydrolyze long chains of triglycerides[1]. Lipase is a water-soluble enzyme and naturally lipase catalyze the hydrolysis of ester bonds in water insoluble lipid substrate and long-chain acylglycerol synthesis, diacylglycerol, monoacylglycerol, and glycerol[2]. Hydrolase enzyme lipase can be used potentialy produced fatty acid which precursors in the chemical industry[3]. The research aims to study the lipolytic activity of bacteria isolated from soil contaminated with oil. Screening of lipolytic bacteria was performed in Rhodamin-B agar plate containing olive oil. The lipolytic activity was determined by spectrofotometry method toward p-nitrofenil palmitat as a substrate. The result this research showed that there are 15 of 150 isolates bacteria from soil contaminated with oil was confirmed by observing the zone of hydrolysis formed around the growth of colony on Rhodamin B agar plate containing olive oil. One of the lipolytic bacteria identified as higher activity was produced lipase with activity of 7,41 U/ml
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.