The emergence of antibiotic-resistant pathogens has threatened not only our ability to deal with common infectious diseases but also the management of life-threatening complications. Antimicrobial resistance (AMR) remains a significant threat in both industrialized and developing countries alike. In Africa, though, poor clinical care, indiscriminate antibiotic use, lack of robust AMR surveillance programs, lack of proper regulations and the burden of communicable diseases are factors aggravating the problem of AMR. In order to effectively address the challenge of AMR, antimicrobial stewardship programs, solid AMR surveillance systems to monitor the trend of resistance, as well as robust, affordable and rapid diagnostic tools which generate data that informs decision-making, have been demonstrated to be effective. However, we have identified a significant knowledge gap in the area of the application of fast and affordable diagnostic tools, surveillance, and stewardship programs in Africa. Therefore, we set out to provide up-to-date information in these areas. We discussed available hospital-based stewardship initiatives in addition to the role of governmental and non-governmental organizations. Finally, we have reviewed the application of various phenotypic and molecular AMR detection tools in both research and routine laboratory settings in Africa, deployment challenges and the efficiency of these methods.
Kazakhstan announced the first cases of COVID‐19 in March 2020. Within a span of a few months, the pandemic ravaged all regions affecting vulnerable populations due to limited access to healthcare services and co‐morbidities. To minimize the spread of the pandemic, the government announced the implementation of containment measures such as quarantine, movement restrictions, and lockdowns among others. The collateral effect of the pandemic has disrupted economic and learning activities pushing several people below the poverty line. The pandemic revealed the weakness of healthcare including the acute shortage of essential medicines and lack of hospital beds. This calls for stringent measures to revive the economy and mitigate the reeling effect of the pandemic. As a result, Kazakhstan commenced COVID‐19 vaccination efforts in February 2021. To date, about 47.8% are fully vaccinated pushing Kazakhstan closer to achieving herd immunity at the 60% threshold. However, the country faces challenges such as vaccine hesitancy and uncertainty surrounding vaccine effectiveness against new variants of SARS‐CoV2, among others. This paper aims to explore the health and socioeconomic challenges caused by COVID‐19 in Kazakhstan, control strategies, vaccination campaigns and progress towards herd immunity.
On 23 July 2022, the World Health Organization reported monkeypox cases in over 75 countries and, as a result, declared the virus a Public Health Emergency of International Concern (PHEIC). Despite Africa being the centre of the zoonotic disease evolution, its healthcare systems have not provided optimum attention to the problem. The African healthcare system is under the threat of a repeat of the situation that transpired during the COVID-19 pandemonium if stringent measures are not implemented immediately. Lessons learned from the COVID-19 pandemic should inform emergency preparedness and response from African countries. Concerted and sustainable efforts can be achieved by reviewing and redesigning strategic preparedness plans for testing and vaccination as in previous pandemics. Africa needs to drive this response with collaboration and a united response, and with the use of strategic communication and a sense of urgency. Africa should prioritise access to available vaccines and invest in systems development for local vaccine production. In this article, we argue that monkeypox virus has serious public health implications in Africa and the region.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.