Objectives The objective of this study is to examine the performance of Ductus venosus (DV) Doppler done at the routine first trimester screening (11–13 + 6 weeks) in predicting the adverse fetal outcomes in Indian population. Methods This observational study was conducted between 2013 and 2019, on 4340 singleton pregnancies. Ductus Doppler were considered abnormal if DV pulsatility index values were >95th centile for that gestation or with a reversed “a” wave. Anatomical survey was done to rule out other abnormalities. Women were followed up till delivery and outcomes were divided into 4 groups: 1) aneuploidies; 2) cardiac defects; 3) non‐cardiac structural abnormalities; and 4) miscarriages before 24 weeks or fetal deaths after 24 weeks. Results Prevalence of abnormal DV Doppler is 5.12% (205/4004). There were significantly higher number of fetal losses (4.4 versus 0.3%), aneuploidies (10.2 versus 1.7%), fetal cardiac defects (5.9 versus 1.4%), and non‐cardiac structural defects (5.4 versus 1.4%) among the pregnancies with abnormal DV Doppler in comparison to those with normal flow (P < .001). Logistic regression analysis has shown that significant contribution to fetal chromosomal abnormalities and cardiac defects was associated with abnormal DV. Other factors which were found to have a significant association with adverse fetal outcome were increased nuchal translucency and increased body mass index (BMI). Conclusion DV Doppler in first trimester can be used as a screening tool for cardiac defects and fetal deaths. Women with abnormal DV Dopplers should be offered fetal echocardiography at 18–22 weeks and third trimester growth scans with Dopplers.
Virtual poster abstracts subdiaphragmatic bronchopulmonary sequestration. Fetal abdominal mass continued to grow to 4.7 x 3.0 cm at 35weeks of gestation. When a woman came to delivery unit due to labour pain at 38 weeks' gestation, the size of mass increased to 5.1 X 3.5 cm with mixed echogenicity and hepatomegaly was accompanied. After a vaginal delivery, postnatal ultrasonography and MRI revealed a left suprarenal space neuroblastoma, multiple liver metastasis with marked hepatomegaly, and splenomegaly. Poorly differentiated neuroblastoma was diagnosed on excision biopsy. Although most of stage 4s neuroblastoma shows good prognosis, rapid growing mass and hepatomegaly, followed by abdominal expansion and dyspnea are considered as a main obstacle to full patient cure. We conclude that a prenatal rapid growing mass in suprarenal area, which is suggestive of neuroblastoma, requires close monitoring with disease staging. Planned delivery may be considered for prompt neonatal treatment, because disease progression can be overwhelmingly rapid. VP11.16 Multicystic dysplasic kidney: postnatal involution and compensatory hypertrophy
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