UNUSUAL VARIANTS OF FIBROADENOMA BREAST DIAGNOSED ON CYTOLOGYFibroadenomas are common benign breast tumours that display a characteristic morphology, although several epithelial and stromal variations exist which may pose a diagnostic difficulty. We are discussing a case series of four cases of benign fibroadenoma with morphological variations as observed on cytology smears in the department of Pathology, KGMU, Lucknow, UP. Juvenile fibroadenoma constitutes only 4% of the total fibroadenomas with incidence of 0.5% per year.Another very rare histological finding is the presence of multinucleated giant cells throughout the stroma of a benign fibroadenoma, more commonly found incidentally within the interlobular stroma of breast tissue. Similarly apocrine metaplasia has been found to be 28% in a case series (Arno Kuijper et.al) of 396 cases of fibroadenoma.It is important to identify these variants as they may be misinterpreted as malignancy.
Endometriosis occurring in a surgical scar is called incisional endometriosis. It is rare and can be diagnosed on the basis of detailed history, careful clinical examination and characteristic histology. An interesting case with immunocytological (ICC) confirmation is being reported. A 28-year-old female presented with a mass over anterior abdominal wall, of 3 years duration. She had a past history of LSCS. On examination, the swelling was subcutaneous, measures 3x2cm was firm in consistency and located close to the previous incisional scar. Fine needle aspiration cytology was performed and the smears were moderately cellular and showed monolayered sheets of epithelial cells and stromal fragments. A cell block was also prepared that revealed few glands lined by tall columnar epithelium, surrounded by loose stroma. Immunohistochemistry panel comprising of CK 7 and CD 10 was performed, which were positive in glandular and stromal component respectively.
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