The purpose of this study was to compare the effect of Phacoemulsification and Manual small incision cataract surgery (MSICS) on the corneal endothelium and to assess its impact on visual acuity and induced astigmatism. In this prospective randomized study, 100 cases were randomly selected with the help of lottery system. 50 cases underwent phacoemulsification (group 1) and 50 underwent MSICS (group 2) by a single surgeon. The endothelial cell count, central corneal thickness, best corrected visual acuity and induced astigmatism was measured preoperatively and postoperatively on day 1, 7, 28 and on day 42. Mean endothelial cell loss (cells/mm2) in group 1 at the end of six weeks was 538.64 (20.59%) and in group 2 was 485.66 (19.20%) which was statistically insignificant (p >0.05). The mean central corneal thickness was reduced in both the groups with a mean of 0.51±0.04 mm in group 1 and 0.50±0.03 mm in group 2 which was statistically insignificant. Postoperative best corrected visual acuity of more than 6/18 was found in 49 (98%) cases in each group at six weeks, and was statistically insignificant (p value > 0.05). Phacoemulsification group had statistically significant less mean postoperative astigmatism than MSICS group (p value < 0.05). Both groups gave similar statistically insignificant results in relation to endothelial cell loss, central corneal thickness and best corrected visual acuity at the end of six weeks, although the mean astigmatism was more in group 2 in comparison to group 1 with a statistically significant difference.
Systemic lupus erythematosus is a multisystem autoimmune disorder and its complications include cerebral vasculitis and vasculopathy which can be the first manifestation of SLE. Subarachnoid haemorrhage due to rapid aneurysm growth and rupture is a major neurosurgical emergency associated with significant morbidity and mortality. There is need for more rapid diagnosis and aggressive treatment of SLE patients with unruptured aneurysms. Authors report a case of 23 years old female, a newly diagnosed case of SLE complicated by rupture of cerebral aneurysms.
Retinopathy of prematurity (ROP) is one of the major cause of the preventable childhood blindness worldwide. One year
prospective interventional study was conducted in a tertiary care centre in Northern India. All neonates with birth weight ≤
2000 grams with gestational age ≤35 weeks were screened for ROP and divided into two groups, infants with birth weight <1750 grams (Group A)
and ≥1750 grams (Group B). Prevalence of ROP, risk factors and laser treatment outcomes were compared between two groups. Of 191 neonates
screened, 61(31.93%) developed ROP, out of which Infants with very low birth weight were at signicantly higher risk of developing severe ROP
requiring treatment. In addition, high concentration and uctuating oxygen administration, sepsis, shock, intravenous uids >10 days were
observed to be statistically signicant risk factors in infants <1750 grams. Timely screening and early treatment of threshold ROP results in
desirable structural and functional outcome.
Central Serous Chorioretinopathy(CSCR) is predominantly idiopathic and self limiting macular disease . Present study
was planned to determine clinical prole and the factors contributing in nal visual outcome in CSCR.. Retrospective
observational study was done on 65 eyes of 53 patients over a period of 2 years. Their best corrected visual acuity(BCVA), color vision,
metamorphopsia and mean central macular thickness(CMT) at presentation were compared with values at 6 months follow-up. Mean age of
patients was 38 years ± 5.43 years. 79.24% patients were males and 77.36% had unilateral involvement. 30.19% patients gave history suggestive
of one or more potential risk factors. The mean BCVA improved from 20/80 at presentation to 20/20 and 20/25 in patients with isolated and CSCR
with PED respectively at 6 months. The mean CMT reduced signicantly in both isolated CSCR and when associated with PED at 6 months.
Color vision defects in 46(70.77%) eyes and metamorphopsia in 49(75.38%) eyes at presentation persisted in 7(10.7%) eyes and 20(30.76%)eyes
respectively at 6 months. Final visual outcome signicantly correlated with visual acuity at presentation.
CONCLUSION: BCVA at presentation strongly predicts nal visual prognosis. Patients need to be counselled regarding persistence of color
vision decits and metamorphopsia.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.