This is the first report of SIV/HIV-2 chimeras that are infectious in macaques. Moreover, this is the first report of an infectious chimera in which both SIV gag and pol have been replaced with the equivalent regions of an HIV isolate.
Int Clin Pathol J 2017, 5(2): 00128
AbstractThe anatomical and histo pathological state of chronic liver diseases is a balance between the effects of liver injury and repair. As cirrhosis develops and progress the fibrous bands tends to be thick and widened with evidence of histological activity and Cirrhosis is more of a macro nodular pattern. If the cause of ensuing liver injury is removed or if effective treatment of underlying liver injury diseases are ensured, regeneration of hepatocytes dominates over fibrosis resulting enlargement of regenerative nodules and expansion against septae as well as lyses of sepate. Nodules surrounded by thin sepate then coalesce first giving rise to macro nodular pattern cirrhosis. Incomplete septal cirrhosis is morphological land mark in this dynamic process of regeneration and repair and thus these authors postulate that incomplete cirrhosis is a feature of regressing cirrhosis rather than a separate entity as it was told by Poper H [1].
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