Background:Smaller substances <600 Daltons (Da) can transit human placenta while larger ones >1000 Da may not. This may not be consistent because maternal measles antibodies (MMA) are large immunoglobulin G molecules with molecular weight of 150,000 Da, could cross the placenta in mother-infant pairs.Aim:The objective was to assess the efficiency of placental transfer of MMA in mother-infant pairs at birth.Subjects and Methods:Sera collected from mother-infant pairs were analyzed for MMA using enzyme-linked immunosorbent assay. Gestational age (GA) of newborns was determined using the last menstrual period, ultrasound scan, and the Dubowitz criteria, whereas their birth weight (BW) was measured using the bassinet weighing scale.Results:Correlation coefficient (r) of MMA of mother-infant pairs at birth was significant (P < 0.01) and comparison of mean MMA for term and postterm deliveries were significant (P = 0.001) and (P = 0.007) respectively. Goodman and Kruskal's Gamma rank correlation of GA and BW was also significant (P< 0.001).Conclusion:Passage of MMA across placenta was efficient and newborn infants are protected from measles at birth.
Intestinal duplication is one of the rare congenital abnormalities encountered. Duplications found on the small intestine are more commonly encountered in clinical practice than the large intestine and majority of these occurs in the ileum. We present a three-week old neonate with features of intestinal obstruction a presumptive diagnosis of intususception with presumed sepsis was made.Intraoperative findings revealed caecal duplication causing the intestinal obstruction. Limited excision and ileo-ascending colic anastomosis was carried out. Patient responded well and was discharged on follow-up.
Background: Maternal measles antibodies (MMA) are actively transferred in mother-infant pairs during third trimester of pregnancy. Gestational age (GA) affects the levels of MMA such that longer GA may result in infants starting out with high levels of MMA.
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