The SARS-CoV-2-infection can be seen as a single disease but also affects patients with relevant comorbidities who may have an increased risk of a severe course of infection. In this report, we present a 77-year old patient with a heart transplant under relevant immunosuppressive therapy who was tested positive for SARS-CoV-2 after several days of dyspnoea, dry cough and light general symptoms. The CTscan confirmed an interstitial pneumonia. The patient received an antiviral therapy with hydroxychloroquine showing no further deterioration of the clinical state. After 12 days of hospitalisation the patient was released SARS-CoV-2 negative and completely asymptomatic.
Anamnesis
Accepted Article
The National Cancer Institute (NCI) Cancer Research Data Commons (CRDC) aims to establish a national cloudbased data science infrastructure. Imaging Data Commons (IDC) is a new component of CRDC supported by the Cancer Moonshot™. The goal of IDC is to enable a broad spectrum of cancer researchers, with and without imaging expertise, to easily access and explore the value of de-identified imaging data and to support integrated analyses with non-imaging data. We achieve this goal by co-locating versatile imaging collections with cloudbased computing resources and data exploration, visualization, and analysis tools. The IDC pilot was released in October 2020 and is being continuously populated with radiology and histopathology collections. IDC provides access to curated imaging collections, accompanied by documentation, a user forum, and a growing number of analysis use cases that aim to demonstrate the value of a data commons framework applied to cancer imaging research.Significance: This study introduces NCI Imaging Data Commons, a new repository of the NCI Cancer Research Data Commons, which will support cancer imaging research on the cloud.
The data indicate that there are differences in the electrophysiological properties of retinal capillary pericytes of 5-7 days old RCS and control rats. Whereas resting membrane voltage and K+ conductance are comparable in both groups, there are significant differences in the electrical activity of Na(+)-K(+)-ATPase and in the effects of vasoactive substances on the membrane voltage and currents. These differences might contribute to the vascular changes observed in RP, and possibly accelerate the progress of retinal dystrophy.
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