Reduction and Isomerization of Oxiranes and α-Diazo Ketones byVarious Early Transition Metallocenes. -Niobocene, generated in situ by dehalogenation of niobocene dichloride with one equivalent magnesium in tetrahydrofuran, reduces the oxiranes (I) and (IV) to yield the alkenes (II) and (III) or the hexa-1,5-diene (V). The ketones (VII) are prepared by reduction of the α-diazo ketones (VI) with niobocene. Reactive titanocene in THF converts β -pinene oxide (VIII) to the aldehyde (IX). Further reductions with metallocenes are reported. -(SCHOBERT, R.; HOEHLEIN, U.; Synlett (1990) 8, 465-466; Inst. Org. Chem., Univ. Erlangen-Nuernberg, W-8520 Erlangen, Germany; EN)
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.