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Caralluma sarkariae is a succulent, endangered and endemic plant from southern Western Ghats. This species has used by ethanomedicinal practices by traditional healers of Southern Tamilnadu. Traditionally the plant has been used as the treatment of Rheumatism, ulcer, asthma, fever, inflammation, diabetes, stress, cancer and obesity. The methanolic extract of C. sarkariae was investigated for Anti-diabetic activity by STZ induced male wistar albino rats. The result indicated that the methanolic extract at the dose of 150mg/kg b.wt., showed a Significant anti-diabetic activity as compared to the standard drug. The findings of the study suggest that the methanolic extract of C. sarkariae showed significant activities which confirm the traditional usage of this medicinal plant to treat the metabolic disorders.

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The present study, investigates themethanolicleaves extract of Wattakaka volubilis (Family: Asclepiadaceae) designated as 'the extract' was evaluated for analgesic activity in mice. The analgesic activity was evaluated in mice models. In the acute toxicity study, it was found that the extract was non-toxic up to 1000mg/kg, p. o. The extract (150, 200 and 400 mg/kg, p. o.) was found to possessanalgesic activities in a dose-dependent manner and the effect was comparable with thatproduced by the standard drug, Diclofenac sodium.

Stephania wightii is an endemic medicinal plant traditionally used in India for various ailments. This study was set out to evaluate the aphrodisiac properties of methanolic aerial parts and tuber extracts of Stephania wightii using animal models. The methanolic tuber extract of S. wightii at the dose of 100 mg/kg body weight showed significant aphrodisiac activity on male wistar albino rats as evidenced by an increased the levels of reproductive hormones serum testosterone, Serum Luteinizing hormone and Serum Follicle-stimulating hormone. The efficiency was higher in the extract treated animals compared to the standard drug treated animal.