Schiff base derived from salicylaldehyde and 2,4-dinitrophenylhydrazine was synthesized. Its Mn(II) and Fe(II) complexes (MnL2 and FeL2) were synthesized by refluxing the metal (II) chlorides with the Schiff base. All the compounds were characterized by melting point/decomposition temperature, solubility, molar conductance, magnetic susceptibility infrared analysis and UV - visible spectrophotometry. The composition of the complexes has been found to be 1:2 (Metal-Ligand) ratio. The complexes have low molar conductance values 6.39 -6.59 ohm-1 cm2 mol-1 indicating non-electrolytes. The Schiff base and its metal (II) complexes were screened for antibacterial          activity against five bacterial isolates Escherichia coli, Proteus mirabilis, Klebsiella           pneumonia, Pseudomonas aureginosa and Staphylococcus aureus and three fungal isolates Fusarium solani, Aspergillus fumigates and Candida Albicans using good method. The results revealed that the complexes showed higher activity against the microorganisms compared to the Schiff base.