No abstract

Ulcerative colitis (UC) is an inflammatory bowel disease characterized by chronic mucosal inflammation of the colon, and the prevalence and incidence of UC have been steadily increasing in Taiwan. A steering committee was established by the Taiwan Society of Inflammatory Bowel Disease to formulate statements on the diagnosis and management of UC taking into account currently available evidence and the expert opinion of the committee. Accurate diagnosis of UC requires thorough clinical, endoscopic, and histological assessment and careful exclusion of differential diagnoses, particularly infectious colitis. The goals of UC therapy are to induce and maintain remission, reduce the risk of complications, and improve quality of life. As outlined in the recommended treatment algorithm, choice of treatment is dictated by severity, extent, and course of disease. Patients should be evaluated for hepatitis B virus and tuberculosis infection prior to immunosuppressive treatment, especially with steroids and biologic agents, and should be regularly monitored for reactivation of latent infection. These consensus statements are also based on current local evidence with consideration of factors, and could be serve as concise and practical guidelines for supporting clinicians in the management of UC in Taiwan.

Crohn's disease (CD) is a chronic relapsing and remitting inflammatory disease of the gastrointestinal tract. CD is rare in Taiwan and other Asian countries, but its prevalence and incidence have been steadily increasing. A steering committee was established by the Taiwan Society of Inflammatory Bowel Disease to formulate statements on the diagnosis and management of CD taking into account currently available evidence and the expert opinion of the committee. Thorough clinical, endoscopic, and histological assessments are required for accurate diagnosis of CD. Computed tomography and magnetic resonance imaging are complementary to endoscopic evaluation for disease staging and detecting complications. The goals of CD management are to induce and maintain remission, reduce the risk of complications, and improve quality of life. Corticosteroids are the mainstay for inducing re-mission. Immunomodulating and biologic therapies should be used to maintain remission. Patients should be evaluated for hepatitis B virus and tuberculosis infection prior to treatment and receive regular surveillance for cancer. These consensus statements are based on current local evidence with consideration of factors, and could be serve as concise and practical guidelines for supporting clinicians in the management of patients with CD in Taiwan.

No abstract

Interrelations between lactation and post-partum amenorrhea are studied from the reports of about 5,000 married women included in a 1966 Follow-up Survey of Acceptors of an Intrauterine Device (IUD) in Taiwan. The length of post-partum amenorrhea and of breastfeeding are positively associated. On an average, breastfeeding delayed the resumption of menstruation by about 7 months. The association between lactation and amenorrhea is not accounted for by differences in mother’s age, parity, education and her place of residence. A multiple regression analysis suggests that (1) age affects amenorrhea both directly and through lactation, (2) parity has no independent effect on either lactation or amenorrhea, and (3) education and place of residence affect amenorrhea mainly through the cultural variations in the practice of breastfeeding.

As advances in cancer therapy bring about a progressively larger percentage of long-term survivors, the proportion of patients with subsequent primary lesions will increase. Early diagnosis of these lesions, based on an awareness of the possibility of second and third cancers, and multidisciplinary treatment strategies will substantially increase the survival of these patients.

This experience suggests that an anastomosis can be performed more safely in patients with acute obstruction of the left colon than in those with an anastomosis in the nondiverted colon. Neither intraoperative irrigation nor routine subtotal colectomy was found to be necessary. Anastomosis below the peritoneal reflection is also not a contraindication.

A realistic model for friction in lubricated sheet-metal forming which takes account of the different lubrication regimes which may occur at the sheet/tooling interface is developed. Friction is expressed in terms of internal interface variables (mean lubricant film thickness, sheet roughness and tooling roughness) in addition to the more traditional external variables (interface pressure, sliding speed and strain rate). The new model has been coupled to an existing finite element membrane analysis of axisymmetric stretch forming. Numerical results using the coupled codes showed excellent agreement with measured strain distributions over a range of operating conditions. Computational times with the refined friction model were typically increased by about 10 percent compared to those with a simple Amontons-Coulomb constant friction coefficient model.