Prehypertension is very common among Israeli adolescents. A substantial number of adolescents exhibit a BMI greater than normal. As both of these factors are known to be asssociated with increased cardiovascular risk, early institution of healthful lifestyle changes in a large proportion of this age group is recommended.

The risk of developing hypertension in young adulthood may be predicted by BP categories and BMI at adolescence.

BackgroundSBRT is standard therapy for early stage lung cancer. Toxicity in central tumors has been a concern. RTOG 0813 showed that central SBRT is safe and effective. We report our experience with central SBRT.MethodsWe reviewed the records of patients treated with SBRT for central lung tumors (< 2 cm of the carina). Patients included primary lung cancer and recurrence following surgery and\ or conventional radiotherapy. All patients underwent 4DCT simulation and treatment planning was done with IMRT or VMAT techniques. Dose to the PTV was prescribed to the 95% isodose line.ResultsSeventy patients, between 5/09 and 4/13, were treated. Patients had early non-small cell lung cancer (n = 13) or locally recurrent lung cancer (n = 29) and pulmonary oligometastases (n = 28). Fifty-seven percent of the patients received BED of 132 with a schedule of 60Gy in 12 Gy fractions. Median follow up time was 18.3 months, 4/70 patients experienced local failure (6%). Median OS for the whole cohort was 4.6 years (CI 3-7 years). Ten patients had grade 1-2 radiation pneumonitis. One patient developed fatal bronchial bleeding.ConclusionsSBRT for central tumors is safe and effective in patients with central disease, reiradiation, recurrence following surgery and in oligometastes.