Saxen L, Viljanen T, Westermarck T: Occurrence of caries and periodontal disease in seleniumtreated patients with Spielmeyer-Sjogren's disease. ScandJ Dent Res 1983; 91: 356-9.Abstract -The possible influence of continuous exposure to selenium on dental caries and gingivitis was examined during a clinical trial of selenium administration to patients suffering from a progressive encephalopathy, Spielmeyer-Sjogren's disease. The study group consisted of eight children (mean age 12.5 years) and a control group ofthe same age and size from the same institution. DMFS-and Gingival Bleeding Indices were recorded at the onset of the selenium medication and thereafter once a year. No dilierence in the caries incidence or in the prevalence of gingivitis between the two groups could be shov^n during the follow-up period.
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