No abstract

16 children, 9 male and 7 female, underwent injection laryngoplasty for LC-1. Mean gestational age at birth was 35.5 weeks (SD 4.0, range 27-41 weeks). Six patients had a major congenital anomaly (37.5%). Mean age at injection was 11.8 months (SD 8.9, range 2.9 to 33.5 months). 9 patients (56.3%) experienced complete resolution of penetration and aspiration based on postoperative modified barium swallow (MBS), 4 patients (25%) had improvement in symptoms, and 2 patients (12.5%) had no change in symptoms. 1 patient did not have postoperative swallowing evaluation. There were no complications. Mean duration of symptom improvement was 2.8 months (SD 1.7, range 0-6 months). Four patients went on to have definitive surgical LC-1 repair. CONCLUSION: Injection laryngoplasty was found to be safe and efficacious in this group of patients with LC-1. The majority of patients experienced complete resolution of aspiration on MBS. Further studies with a longer follow-up interval are necessary to elucidate the predictive value with regard to success of formal cleft repair.