In this work, we designed and developed a method to detect S1 spike protein of SARS-CoV-2. The portable Localized Surface Plasmon Resonance instrument equipped with a two-channel system was combined...
Microplastics (MPs) are a part of our daily lives and persist in the environment all across the globe. As a recently recognized emerging pollutant, there is a call to action to mitigate and monitor microplastics. Despite traditional remediation and characterization methodologies, MP-related challenges still exist. Electrochemical strategies for microplastic remediation have been reported in recent years, but very few reports exist on using electrochemical sensors for monitoring microplastics. Therefore, this minireview highlights the opportunities within the existing electrochemical remediation platforms towards sensor design and development, and elaborates on microplastic electrochemical sensors so far.
This work describes the differential quenching of molecular oxygen and superoxide anion radical (O2˙–) by (metallo)‐quercetin (QCR) complexes. The in situ complexes were more reactive with molecular oxygen than preformed complexes. By adjusting the potential range, it was determined that Cu2+ complexes exhibited similar superoxide anion radical (O2˙–) quenching ability as free QCR. The Fe3+ complexes were less reactive than free QCR or Cu2+ complexes. The data indicate that metal ions significantly modulated reactivity of QCR with O2˙– or molecular oxygen, and may regulate antioxidant activity and reactive oxygen species levels in a complex biological setting.
This article provides a brief overview of how electrochemical methods are applied in analysis of neurodegeneration biomarkers, their biochemistry and detection. It introduces the basic concepts of solution- or surface-based electrochemical methods to probe self-assembly and aggregation of peptides and proteins. The label-free approach is applied to analysis of neurotransmitters and peptides, such as Amyloid-β and α-synuclein, with inherent redox active amino acids. It also highlights the labeled approaches for detection of enzyme-catalyzed transformations of neuronal proteins, such as tau. Given the flexibility of electrochemical methods, the detection of interactions between metal ions and biomolecules of the brain has also been demonstrated.
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