Highlights
Spontaneous dog cancers closely resemble human cancer.
Dogs with EGFR associated tumors were immunized with an EGFR/HER2 peptide vaccine.
EGFR peptide vaccinated dogs developed anti-EGFR/HER2 antibodies.
Vaccinated dogs have anti-EGFR antibody and T cells infiltrating tumors.
Vaccinated dogs with osteosarcoma had tumor regression and increased survival.
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